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Influence of a fed or fasted state on the s-IgA response to prolonged cycling in active men and women

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posted on 2012-10-05, 10:28 authored by Judith E. Allgrove, Louise Geneen, Sarah Latif, Michael Gleeson
This study investigated the effect of a fed or fasted state on the salivary immunoglobulin A (s-IgA) response to prolonged cycling. Using a randomized, crossover design, 16 active adults (8 men and 8 women) performed 2 hr of cycling on a stationary ergometer at 65% of maximal oxygen uptake on 1 occasion after an overnight fast (FAST) and on another occasion 2 hr after consuming a 2.2-MJ high-carbohydrate meal (FED). Timed, unstimulated whole saliva samples were collected immediately before ingestion of the meal, immediately preexercise, 5 min before cessation of exercise, immediately postexercise, and 1 hr postexercise. The samples were analyzed for s-IgA concentration, osmolality, and cortisol, and saliva flow rates were determined to calculate s-IgA secretion rate. Saliva flow rate decreased by 50% during exercise (p < .05), and s-IgA concentration increased by 42% (p < .05), but s-IgA secretion rate remained unchanged. There was a 37% reduction in s-IgA:osmolality postexercise (p < .05), and salivary cortisol increased by 68% (p < .05). There was no effect of FED vs. FAST on these salivary responses. The s-IgA concentration, secretion rate, and osmolality were found to be significantly lower in women than in men throughout the exercise protocol (p < .05); however, there was no difference between genders in saliva flow rate, s-IgA:osmolality ratio, or cortisol. These data demonstrate that a fed or fasted state 2 hr before exercise does not influence resting s-IgA or the response to prolonged cycling. Furthermore, these results show lower levels of s-IgA and osmolality in women than in men at rest.

History

School

  • Sport, Exercise and Health Sciences

Citation

ALLGROVE, J.E. ... et al., 2009. Influence of a fed or fasted state on the s-IgA response to prolonged cycling in active men and women. International Journal of Sport Nutrition and Exercise Metabolism, 19 (3), pp. 209 - 221.

Publisher

© Human Kinetics, for the International Society of Sport Nutrition

Version

  • VoR (Version of Record)

Publication date

2009

Notes

This article was published in the journal, International Journal of Sport Nutrition and Exercise Metabolism [© Human Kinetics] and the definitive version is available from PubMed at http://www.ncbi.nlm.nih.gov/pubmed/19574610. The publisher's website is at: http://journals.humankinetics.com/

ISSN

1526-484X

Language

  • en

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