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Physical activity and risk of all-cause and cardiovascular disease mortality in diabetic adults from Great Britain: pooled analysis of 10 population-based cohorts
journal contribution
posted on 2015-10-29, 12:04 authored by K.P. Sadarangani, Mark Hamer, J.A. Mindell, Ngaire A. Coombs, Emmanuel StamatakisOBJECTIVE
To examine associations between specific types of physical activity and all-cause
and cardiovascular disease (CVD) mortality in a large nationally representative
sample of adults with diabetes from Great Britain.
RESEARCH DESIGN AND METHODS
There were a total of 3,038 participants (675 deaths) with diabetes in the Health
Survey for England and the Scottish Health Surveys conducted between 1997
and 2008. Participants aged ‡50 years at baseline were followed up for an average
of 75.2 months for all-cause and CVD mortality. Data were collected on selfreported frequency, duration, and intensity of participation in sports and exercise, walking, and domestic physical activity, from which the number of MET-hours/
week were derived. Sex-specific medians of time spent in each type of physical
activity (for those physically active)were calculated, and Cox proportional hazards
regression conducted to examine type-specific associations between the level of
physical activity and all-cause and CVD mortality risk.
RESULTS
Inverse associations with all-cause and CVD mortality were observed for overall
physical activity in a dose-response manner after adjusting for covariates.
Compared with those who individuals were inactive, participants who reported
some activity, but below the recommended amount, or who met the physical
activity recommendations had a 26% (95%CI 39–11) and 35%(95% CI 47–21) lower
all-cause mortality, respectively. Similar results were found for below/above
median physical activity levels. Sports and exercise participation was inversely
associated with all-cause (but not CVD)mortality, as were above average levels of
walking. Domestic physical activity was not associated with mortality.
CONCLUSIONS
Moderate physical activity levels were associated with better prognosis in diabetic
adults.
History
School
- Sport, Exercise and Health Sciences
Published in
Diabetes CareCitation
SADARANGANI, K.P., ...et al., 2014. Physical activity and risk of all-cause and cardiovascular disease mortality in diabetic adults from Great Britain: pooled analysis of 10 population-based cohorts. Diabetes Care, 37(4), pp. 1016-1023Publisher
© American Diabetes AssociationVersion
- VoR (Version of Record)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 Unported (CC BY-NC-ND 3.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by-nc-nd/3.0/Publication date
2014Notes
This is an Open Access Article. It is published by American Diabetes Association under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 Unported (CC BY-NC-ND 3.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by-nc-nd/3.0/ISSN
1935-5548Publisher version
Language
- en