Wilson_The early career researchers toolkit_Post Review_v1.pdf (309.07 kB)
The early career researcher's toolkit: translating tissue engineering, regenerative medicine and cell therapy products
journal contribution
posted on 2016-11-18, 14:40 authored by Qasim A. Rafiq, Ilida Ortega, Stuart I. Jenkins, Sammy WilsonSammy Wilson, Asha K. Patel, Amanda L. Barnes, Christopher F. Adams, Derfogail Delcassian, David SmithAlthough the importance of translation for the development of tissue engineering, regenerative medicine and cell-based therapies is widely recognized, the process of translation is less well understood. This is particularly the case among some early career researchers who may not appreciate the intricacies of translational research or make decisions early in development which later hinders effective translation. Based on our own research and experiences as early career researchers involved in tissue engineering and regenerative medicine translation, we discuss common pitfalls associated with translational research, providing practical solutions and important considerations which will aid process and product development. Suggestions range from effective project management, consideration of key manufacturing, clinical and regulatory matters and means of exploiting research for successful commercialization.
Funding
The authors would like to acknowledge the support of the Engineering and Physical Sciences Research Council (EPSRC) for the funding of the Engineering, Tissue Engineering and Regenerative Medicine (E-TERM) Landscape Fellowship programme, which involves a partnership of Loughborough, Leeds, Sheffield, Keele, Nottingham and York Universities. All authors, with the exception of D Smith are current E-TERM Fellows or E-TERM alumni. D Smith is a Biomedical Engineer at PCT (a Caladrius Company).
History
School
- Mechanical, Electrical and Manufacturing Engineering
Published in
Regenerative MedicineVolume
10Issue
8Pages
989 - 1003Citation
RAFIQ, Q.A. ... et al, 2015. The early career researcher's toolkit: translating tissue engineering, regenerative medicine and cell therapy products. Regenerative Medicine, 10 (8), pp. 989-1003.Publisher
© Future Medicine LtdVersion
- AM (Accepted Manuscript)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2015Notes
This paper was accepted for publication in the journal Regenerative Medicine and the definitive published version is available at http://dx.doi.org/10.2217/rme.15.56ISSN
1746-0751eISSN
1746-076XPublisher version
Language
- en