Wilson_Terminal sterilization.pdf (368.91 kB)
Terminal sterilization: Conventional methods versus emerging cold atmospheric pressure plasma technology for non‐viable biological tissues
journal contribution
posted on 2017-01-10, 13:25 authored by Nagi M. Marsit, Laura E. Sidney, Matthew J. Branch, Sammy WilsonSammy Wilson, Andrew HopkinsonTissue products are susceptible to microbial contamination from different sources, which may cause disease transmission upon transplantation. Terminal sterilization
using gamma radiation, electron-beam, and ethylene oxide protocols are well established
and accepted, however, such methods have known disadvantages associated with compromised tissue integrity, functionality, safety, complex logistics, availability, and cost. Non-thermal (cold) atmospheric pressure plasma (CAP) is an emerging technology that has several biomedical applications including sterilization of tissues, and the potential to surpass
current terminal sterilization techniques. This review discusses the limitations of
conventional terminal sterilization
technologies for biological materials, and
highlights the benefits of utilizing CAP.
Funding
Funding from The Authority for Research, Science, and Technology of the Ministry of Higher Education and Scientific Research-Libya (Scholarship 404/2013) is gratefully acknowledged.
History
School
- Mechanical, Electrical and Manufacturing Engineering
Published in
Plasma Processes and PolymersCitation
MARSIT, N.M. ...et al., 2017. Terminal sterilization: Conventional methods versus emerging cold atmospheric pressure plasma technology for non‐viable biological tissues. Plasma Processes and Polymers, 14 (7), e1600134.Publisher
© Wiley-VCH VerlagVersion
- AM (Accepted Manuscript)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Acceptance date
2016-11-13Publication date
2017Notes
This is the peer reviewed version of the following article: MARSIT, N.M. ...et al., 2017. Terminal sterilization: Conventional methods versus emerging cold atmospheric pressure plasma technology for non‐viable biological tissues. Plasma Processes and Polymers, 14 (7), e1600134, which has been published in final form at http://dx.doi.org/10.1002/ppap.201600134. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.ISSN
1612-8869Publisher version
Language
- en