Loughborough University
Browse
Thesis-1991-Fairhurst.pdf (6.22 MB)

Stereochemical aspects in the aminoalkylation reactions of ketones

Download (6.22 MB)
thesis
posted on 2018-02-08, 12:52 authored by Robin A. Fairhurst
A simple "one-pot" method has been developed for the amino-methylation of ketones possessing an α-hydrogen under aprotic conditions. The procedure utilises chlorotrimethylsilane in the sequential formation of the intermediate trimethylsilyl enol ether and methylene iminium species. The methylene iminium ion intermediate is generated either from a dialkylaminoalkoxymethane or a bis-(dialkylamino)methane. [Continues.]

Funding

SERC.

History

School

  • Science

Department

  • Chemistry

Publisher

© Robin A. Fairhurst

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 2.5 Generic (CC BY-NC-ND 2.5) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by-nc-nd/2.5/

Publication date

1991

Notes

A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.

Language

  • en

Administrator link

Usage metrics

    Chemistry Theses

    Categories

    Keywords

    untaggedChemical Sciences not elsewhere classified

    Licence

    CC BY-NC-ND 2.5

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC