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Mass transfer resistance in a liquid-phase microextraction employing a single hollow fiber under unsteady-state conditions
journal contribution
posted on 2012-10-03, 13:04 authored by Ksenija R. Kumric, Goran VladisavljevicGoran Vladisavljevic, Jelena S. Dordevic, Jan Ake Jonsson, Tatjana M. Trtic-PetrovicIn this study, the mass transport resistance in liquid-phase microextraction (LPME) in a
single hollow fiber was investigated. A mathematical model has been developed for the
determination of the overall mass transfer coefficient based on the acceptor phase in an
unsteady state. The overall mass transfer coefficient in LPME in a single hollow fiber has
been estimated from time-dependent concentration of extracted analyte in the acceptor
phase while maintaining a constant analyte concentration in the donor phase. It can be
achieved either using a high volume of donor to acceptor phase ratio or tuning the extraction
conditions to obtain a low-enrichment factor, so that the analyte concentration in the
sample is not significantly influenced by the mass transfer. Two extraction systems have
been used to test experimentally the developedmodel: the extraction of Lu(III) from a buffer
solution and the extraction of three local anesthetics from a buffer or plasma solution. The
mass transfer resistance, defined as a reciprocal values of the mass transfer coefficient, was
found to be 1.2 × 103 cm−1 min for Lu(III) under optimal conditions and from 1.96 to
3.3 × 103 cm−1 min for the local anesthetics depending on the acceptor pH and the hydrophobicity
of the drug.
History
School
- Aeronautical, Automotive, Chemical and Materials Engineering
Department
- Chemical Engineering
Citation
KUMRIC, K.R. ... et al, 2012. Mass transfer resistance in a liquid-phase microextraction employing a single hollow fiber under unsteady-state conditions. Journal of Separation Science, 35(18), pp.2390-2398.Publisher
© WILEY-VCH Verlag GmbH & Co. KGaA, WeinheimVersion
- NA (Not Applicable or Unknown)
Publication date
2012Notes
This article is closed access. It was published in the Journal of Separation Science: http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1615-9314ISSN
1615-9306eISSN
1615-9314Publisher version
Language
- en