Synlett alternaramide revised LUPIN.pdf (538.44 kB)
Total synthesis of the marine-derived cyclic depsipeptide alternaramide
journal contribution
posted on 2014-01-09, 15:14 authored by Alexandra E. Horton, Oliver S. May, Mark ElsegoodMark Elsegood, Marc KimberMarc KimberThe first synthesis of the marine fungus derived natural product alternaramide is described using solution phase coupling protocols and via a macrolactonization and macrolactamization route. The structure of alternaramide was confirmed and was supported by single crystal X-ray analysis which exhibited three similar molecules in the asymmetric unit, each with transannular hydrogen bonds.
History
School
- Science
Department
- Chemistry
Citation
HORTON, A.E. ... et al, 2011. Total synthesis of the marine-derived cyclic depsipeptide alternaramide. Synlett, 22 (6), pp. 797 - 800Publisher
© Georg Thieme VerlagVersion
- AM (Accepted Manuscript)
Publication date
2011Notes
This article was published in the journal, Synlett [© Georg Thieme Verlag]. The definitive version is available at: http://dx.doi.org/10.1055/s-0030-1259915ISSN
0936-5214Publisher version
Language
- en