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Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
journal contribution
posted on 2015-10-29, 11:42 authored by Mark Hamer, Roland von Kanel, Manja Reimann, Nico T. Malan, Alta E. Schutte, Hugo W. Huisman, Leone MalanRecent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD)
among urban black South Africans. The aim was to track the progression of CVD risk factors in a multiethnic
sample of South Africans. Participants were 173 black (aged 47.5 ± 7.8 yrs) and 186 white teachers
(aged 49.6 ± 9.9 yrs) that were examined at baseline and 3 years follow-up. Blacks demonstrated a
substantially higher prevalence of composite CVD burden (defined as history of physician diagnosed
heart disease, use of anti-hypertensives, anti-diabetic, or statin medications at either time point)
compared to whites (49.1 vs. 32.0%, p ¼ 0.012) respectively. After controlling for baseline, the black
participants demonstrated greater increases in 24 h systolic and diastolic blood pressure, total cholesterol,
fasting glucose, fibrinogen, D-dimer, and waist circumference in comparison with whites. In
summary, an adverse progression of CVD risk factors was observed in the whole sample, although to a
larger degree in black participants. Aggressive treatment strategies for controlling risk factors in black
Africans are needed to reduce the increasing burden of CVD in South Africa.
Funding
The study was partly funded by The Metabolic Syndrome Institute, France; the Medical Research Council, National Research Foundation, North-West University, and North-West Department of Education, South Africa. MH is supported by the British Heart Foundation (RE/10/005/28296).
History
School
- Sport, Exercise and Health Sciences
Published in
AtherosclerosisCitation
HAMER, M. ... et al., 2014. Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study. Atherosclerosis, 238 (1), pp. 52–54.Publisher
© The Authors. Published by Elsevier Ireland Ltd.Version
- VoR (Version of Record)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 3.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by-nc-sa/3.0/Publication date
2014Notes
This is an open access article under the CC BY-NC-SA license (http://creativecommons.org/licenses/by-ncsa/3.0/).ISSN
1879-1484Publisher version
Language
- en