+44 (0)1509 263171
Please use this identifier to cite or link to this item:
|Title: ||Development of novel drug formulation using microfluidic device|
|Authors: ||Ekanem, Ekanem E.|
Shiu, Yuk Yeung
Henry, John V.
Das, Diganta Bhusan
Vladisavljevic, Goran T.
|Issue Date: ||2012|
|Citation: ||EKANEM, E.E. ... et al, 2012. Development of novel drug formulation using microfluidic device. 11th UK Particle Technology Forum 2012 "Formulating with particles", Loughborough University, 4th-5th April.|
|Abstract: ||Poster introduction: Biosorbable poly(lactic acid) (PLA) microspheres have been used for
controlled drug release, as ultrasound contrast agents, for cell cultivation
in tissue engineering, fabrication of scaffolds, composite coatings, etc.
Coherent PLA particles can be fabricated via single emulsion route. First,
PLA is dissolved in a volatile organic solvent (DCM) and this solution is
emulsified in an aqueous surfactant solution. In the next stage, the
resultant droplets are solidified by evaporation of solvent. Porous PLA
particles can be produced via W/O/W emulsion route, where first, an
inner water phase is dispersed in a mixture of PLA and DCM in the
presence of oil-soluble surfactant form a W/O emulsion. This emulsion is
then dispersed drop-wise into an aqueous surfactant solution to form a
W/O/W emulsion. W/O particles are formed by evaporation of DCM.|
|Description: ||This is a conference poster.|
|Publisher Link: ||http://www.ukptforum.org.uk/|
|Appears in Collections:||Conference Papers and Presentations (Chemical Engineering)|
Files associated with this item:
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.