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Title: Mass transfer resistance in a liquid-phase microextraction employing a single hollow fibre under nonsteady-state conditions
Authors: Kumric, Ksenija R.
Vladisavljevic, Goran T.
Dordevic, Jelena S.
Jonsson, Jan Ake
Trtic-Petrovic, Tatjana M.
Keywords: Hollow fibre liquid-phase microextraction
Mass transfer coefficient
Mass transfer
Issue Date: 2012
Publisher: © Wiley
Citation: KUMRIC, K.R. ... et al., 2012. Mass transfer resistance in a liquid-phase microextraction employing a single hollow fibre under nonsteady-state conditions. Journal of Separation Science, 35 (18), pp.2390–2398.
Abstract: In this study, the mass transport resistance in liquid-phase microextraction in a single hollow fibre (HF-LPME) was investigated. A mathematical model has been developed for the determination of the overall mass transfer coefficient based on the acceptor phase, KA, in an unsteady-state HF-LPME. KA in HF-LPME has been estimated from time-dependent concentration of extracted analyte in the acceptor phase while maintaining a constant analyte concentration in the donor phase. It can be achieved either using a high volume of donor to acceptor phase ratio or tuning the extraction conditions to obtain a low enrichment factor, so that the analyte concentration in the sample is not significantly influenced by the mass transfer. Two HF-LPME systems have been used to test experimentally the developed model: the extraction of Lu(III) from a buffer solution and the extraction of three local anaesthetics from a buffer or plasma solution. The mass transfer resistance, RA, defined as a reciprocal values of KA, was found to be 1.2103 cm-1 min for Lu(III) in HF-LPME under optimal conditions. The RA values for the local anaesthetics were in the range from 1.96 to 3.3 103 cm-1 min, depending on the acceptor pH and the hydrophobicity of the drug.
Description: Closed access. This paper is in press and was accepted for publication in the Journal of Separation Science [© Wiley]. The publisher's website is at: http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1615-9314/
Version: Accepted for publication
DOI: 10.1002/jssc.201200497
URI: https://dspace.lboro.ac.uk/2134/10103
ISSN: 1615-9306
Appears in Collections:Closed Access (Chemical Engineering)

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