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|Title: ||Mass transfer resistance in a liquid-phase microextraction employing a single hollow fibre under nonsteady-state conditions|
|Authors: ||Kumric, Ksenija R.|
Vladisavljevic, Goran T.
Dordevic, Jelena S.
Jonsson, Jan Ake
Trtic-Petrovic, Tatjana M.
|Keywords: ||Hollow fibre liquid-phase microextraction|
Mass transfer coefficient
|Issue Date: ||2012|
|Publisher: ||© Wiley|
|Citation: ||KUMRIC, K.R. ... et al., 2012. Mass transfer resistance in a liquid-phase microextraction employing a single hollow fibre under nonsteady-state conditions. Journal of Separation Science, 35 (18), pp.2390–2398.|
|Abstract: ||In this study, the mass transport resistance in liquid-phase microextraction in a single hollow
fibre (HF-LPME) was investigated. A mathematical model has been developed for the
determination of the overall mass transfer coefficient based on the acceptor phase, KA, in an
unsteady-state HF-LPME. KA in HF-LPME has been estimated from time-dependent
concentration of extracted analyte in the acceptor phase while maintaining a constant analyte
concentration in the donor phase. It can be achieved either using a high volume of donor to
acceptor phase ratio or tuning the extraction conditions to obtain a low enrichment factor, so
that the analyte concentration in the sample is not significantly influenced by the mass
transfer. Two HF-LPME systems have been used to test experimentally the developed model:
the extraction of Lu(III) from a buffer solution and the extraction of three local anaesthetics
from a buffer or plasma solution. The mass transfer resistance, RA, defined as a reciprocal
values of KA, was found to be 1.2103 cm-1 min for Lu(III) in HF-LPME under optimal
conditions. The RA values for the local anaesthetics were in the range from 1.96 to 3.3 103
cm-1 min, depending on the acceptor pH and the hydrophobicity of the drug.|
|Description: ||Closed access. This paper is in press and was accepted for publication in the Journal of Separation Science [© Wiley]. The publisher's website is at:
|Version: ||Accepted for publication|
|Appears in Collections:||Closed Access (Chemical Engineering)|
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