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Title: Daily probiotic's (lactobacillus casei shirota) reduction of infection incidence in athletes
Authors: Gleeson, Michael
Bishop, Nicolette
Oliveira, Marta
Tauler, Pedro
Keywords: Exercise training
Mucosal immunity
Leukocytes
Respiratory illness
Gut microbiota
Issue Date: 2011
Publisher: © Human Kinetics, for the International Society of Sport Nutrition
Citation: GLEESON, M. ... et al., 2011. Daily probiotic's (lactobacillus casei shirota) reduction of infection incidence in athletes. International Journal of Sport Nutrition and Exercise Metabolism, 21 (1), pp. 55 - 64.
Abstract: The purpose of this study was to examine the effects of a probiotic supplement during 4 mo of winter training in men and women engaged in endurance-based physical activities on incidence of upper respiratory-tract infections (URTIs) and immune markers. Eighty-four highly active individuals were randomized to probiotic (n = 42) or placebo (n = 42) groups and, under double-blind procedures, received probiotic (PRO: Lactobacillus casei Shirota [LcS]) or placebo (PLA) daily for 16 wk. Resting blood and saliva samples were collected at baseline and after 8 and 16 wk. Weekly training and illness logs were kept. Fifty-eight subjects completed the study (n = 32 PRO, n = 26 PLA). The proportion of subjects on PLA who experienced 1 or more weeks with URTI symptoms was 36% higher than those on PRO (PLA 0.90, PRO 0.66; p = .021). The number of URTI episodes was significantly higher (p < .01) in the PLA group (2.1 ± 1.2) than in the PRO group (1.2 ± 1.0). Severity and duration of symptoms were not significantly different between treatments. Saliva IgA concentration was higher on PRO than PLA, significant treatment effect F(1, 54) = 5.1, p = .03; this difference was not evident at baseline but was significant after 8 and 16 wk of supplementation. Regular ingestion of LcS appears to be beneficial in reducing the frequency of URTI in an athletic cohort, which may be related to better maintenance of saliva IgA levels during a winter period of training and competition.
Description: This article was published in the journal, International Journal of Sport Nutrition and Exercise Metabolism [© Human Kinetics] and the definitive version is available from PubMed at http://www.ncbi.nlm.nih.gov/pubmed/21411836. The publisher's website is at: http://journals.humankinetics.com/
Version: Published
URI: https://dspace.lboro.ac.uk/2134/10571
ISSN: 1526-484X
Appears in Collections:Published Articles (Sport, Exercise and Health Sciences)

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