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Title: Influence of a fed or fasted state on the s-IgA response to prolonged cycling in active men and women
Authors: Allgrove, Judith E.
Geneen, Louise
Latif, Sarah
Gleeson, Michael
Keywords: Salivary immunoglobulin A
Nutritional status
Saliva flow rate
Issue Date: 2009
Publisher: © Human Kinetics, for the International Society of Sport Nutrition
Citation: ALLGROVE, J.E. ... et al., 2009. Influence of a fed or fasted state on the s-IgA response to prolonged cycling in active men and women. International Journal of Sport Nutrition and Exercise Metabolism, 19 (3), pp. 209 - 221.
Abstract: This study investigated the effect of a fed or fasted state on the salivary immunoglobulin A (s-IgA) response to prolonged cycling. Using a randomized, crossover design, 16 active adults (8 men and 8 women) performed 2 hr of cycling on a stationary ergometer at 65% of maximal oxygen uptake on 1 occasion after an overnight fast (FAST) and on another occasion 2 hr after consuming a 2.2-MJ high-carbohydrate meal (FED). Timed, unstimulated whole saliva samples were collected immediately before ingestion of the meal, immediately preexercise, 5 min before cessation of exercise, immediately postexercise, and 1 hr postexercise. The samples were analyzed for s-IgA concentration, osmolality, and cortisol, and saliva flow rates were determined to calculate s-IgA secretion rate. Saliva flow rate decreased by 50% during exercise (p < .05), and s-IgA concentration increased by 42% (p < .05), but s-IgA secretion rate remained unchanged. There was a 37% reduction in s-IgA:osmolality postexercise (p < .05), and salivary cortisol increased by 68% (p < .05). There was no effect of FED vs. FAST on these salivary responses. The s-IgA concentration, secretion rate, and osmolality were found to be significantly lower in women than in men throughout the exercise protocol (p < .05); however, there was no difference between genders in saliva flow rate, s-IgA:osmolality ratio, or cortisol. These data demonstrate that a fed or fasted state 2 hr before exercise does not influence resting s-IgA or the response to prolonged cycling. Furthermore, these results show lower levels of s-IgA and osmolality in women than in men at rest.
Description: This article was published in the journal, International Journal of Sport Nutrition and Exercise Metabolism [© Human Kinetics] and the definitive version is available from PubMed at http://www.ncbi.nlm.nih.gov/pubmed/19574610. The publisher's website is at: http://journals.humankinetics.com/
Version: Published
URI: https://dspace.lboro.ac.uk/2134/10573
ISSN: 1526-484X
Appears in Collections:Published Articles (Sport, Exercise and Health Sciences)

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