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|Title: ||Mucosal immune responses during court training in elite tetraplegic athletes|
|Authors: ||Leicht, Christof A.|
Goosey-Tolfrey, Victoria L.
|Keywords: ||Oral immune function|
Salivary immunoglobulin A
|Issue Date: ||2012|
|Publisher: ||Nature Publishing Group © International Spinal Cord Society|
|Citation: ||LEICHT, C.A., BISHOP, N.C. and GOOSEY-TOLFREY, V.L., 2012. Mucosal immune responses during court training in elite tetraplegic athletes. Spinal Cord, 50 (10), pp. 760 - 765.|
|Abstract: ||Study design: Experimental study.
Objectives: To examine salivary secretory immunoglobulin A (sIgA) responses and a-amylase activity during court training in highly
trained tetraplegic athletes.
Setting: Loughborough, UK.
Methods: Seven highly trained wheelchair rugby athletes with tetraplegia performed two separate wheelchair rugby court training
sessions, lasting 23 and 41.5min, respectively, with either an aerobic or an interval focus. Timed, unstimulated saliva samples were
obtained pre, post and 30min post exercise and analysed for sIgA and a-amylase. Furthermore, blood lactate concentration and rating
of perceived exertion (RPE) immediately after training were measured.
Results: sIgA secretion rate and a-amylase were unaffected by exercise during both sessions. However, the increases of sIgA
concentration (30 min post exercise: þ67±29%) during the aerobic session were accompanied by decreases in saliva flow rate
( 35±22%). Athletes’ physiological responses to exercise document the highly strenuous nature of the sessions, with blood lactate
concentrations reaching 8.1±1.0 and 8.7±1.6mmol l 1 and RPE reaching 18(17,18) and 16(15,17) for the aerobic and the
interval session, respectively.
Conclusion: Acute bouts of highly strenuous exercise do not have negative impacts on the mucosal immune response in tetraplegic
athletes, nor do they influence the production of a-amylase, a marker of sympathetic nervous activity. This contrasts responses
previously observed in able-bodied athletes. The disruption of the sympathetic nervous system may prevent the downregulation of sIgA
secretion rate following intense exercise, which is a response previously observed in able-bodied athletes.|
|Description: ||Closed Access. This article was published in the journal, Spinal Cord [© International Spinal Cord Society] and the definitive version is available from Nature Publishing Group at: http://dx.doi.org/10.1038/sc.2012.47|
|Publisher Link: ||http://dx.doi.org/10.1038/sc.2012.47|
|Appears in Collections:||Closed Access (Sport, Exercise and Health Sciences)|
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