Watson et al - Institutional Repository-Effect.pdf (518.08 kB)
Effect of exercise and heat-induced hypohydration on brain volume
journal contribution
posted on 2013-01-09, 09:43 authored by Phil Watson, Kay Head, Alain Pitiot, Peter Morris, Ronald J. MaughanPurpose: The aim of the present study was to quantify changes in brain volume
following exercise/heat-induced hypohydration in man. Methods: Eight active men
completed intermittent exercise in a warm environment, until 2.9 ± 0.1 % of body
mass was lost. Subjects remained hypohydrated for two hours following the end of
exercise. Brain volume was measured before, immediately following, and 1h and 2h
after exercise using MRI (Philips 3T Achieva). Measures of subjective feelings and
core body temperature were also monitored. Blood samples were drawn to determine
serum electrolyte concentrations and osmolality and to allow calculation of changes in
blood and plasma volumes. Results: Brain volume was not influenced by
hypohydration (0.2 ± 0.4 %; ES 0.2; P = 0.310). Reductions in ventricular (4.0 ± 1.8
%; ES 4.6; P < 0.001) and CSF (3.1 ± 1.9%; ES 3.3; P = 0.003) volumes were
observed following exercise. Compared with pre-exercise levels, serum osmolality
was elevated throughout the 2h post-exercise period (+10 ± 2 mosmol/kg; P < 0.001).
Core temperature increased from 37.1 ± 0.3oC at rest to 39.3 ± 0.5oC at the end of
exercise (P = 0.001). Conclusions: These data demonstrate that brain volume remains
unchanged in response to moderate hypohydration and the presence of serum
hyperosmolality, suggesting that mechanisms are in place to defend brain volume.
History
School
- Sport, Exercise and Health Sciences
Citation
WATSON, P. ... et al, 2010. Effect of exercise and heat-induced hypohydration on brain volume. Medicine and Science in Sports and Exercise, 42 (12), pp.2197-2204.Publisher
Lippincott, Williams & Wilkins (© American College of Sports Medicine)Version
- AM (Accepted Manuscript)
Publication date
2010Notes
This is a non-final version of an article published in final form in the journal, Medicine and Science in Sports and Exercise: http://journals.lww.com/acsm-msse/ISSN
0195-9131Publisher version
Language
- en