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Title: Synthesis and electrochemical properties of the naturally occurring free radical scavenger carazostatin
Authors: Jackson, P. Mark
Moody, Christopher J.
Mortimer, Roger J.
Issue Date: 1991
Publisher: © The Royal Society of Chemistry
Citation: JACKSON, P.M., MOODY, C.J. and MORTIMER, R.J., 1991. Synthesis and electrochemical properties of the naturally occurring free radical scavenger carazostatin. Journal of the Chemical Society, Perkin Transactions 1, 12, pp. 2941 - 2944.
Abstract: A short synthesis of the naturally occurring free radical scavenger carazostatin 1 starting from indol-3-ylacetic acid is described, the key step being the regiospecific Diels–Alder reaction of the indolopyrone 2 with ethyl trimethylsilylpropynoate. Electrochemical studies on carazostatin and some of its derivatives show it to be more easily oxidised than butylated hydroxytoluene (BHT).
Description: This article is closed access, it was published in the serial Journal of the Chemical Society, Perkin Transactions 1 [© The Royal Society of Chemistry]. The definitive version is available at: http://dx.doi.org/10.1039/p19910002941
Version: Published
DOI: 10.1039/p19910002941
URI: https://dspace.lboro.ac.uk/2134/11483
Publisher Link: http://dx.doi.org/10.1039/p19910002941
ISSN: 0300-922X
Appears in Collections:Closed Access (Chemistry)

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