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Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/13370

Title: A validated model of GAG deposition, cell distribution, and growth of tissue engineered cartilage cultured in a rotating bioreactor
Authors: Nikolaev, N.I.
Obradovic, B.
Versteeg, Henk K.
Lemon, G.
Williams, David J.
Keywords: Mathematical model
Cartilage tissue engineering
Tissue growth
Cell distribution
Glycosaminoglycan deposition
Cell distribution
Issue Date: 2010
Publisher: © John Wiley and Sons
Citation: NIKOLAEV, N.I. ... et al, 2010. A validated model of GAG deposition, cell distribution, and growth of tissue engineered cartilage cultured in a rotating bioreactor. Biotechnology and Bioengineering, 105 (4), pp.842-853.
Abstract: The purpose of this article is to review the different strategies for the delivery of plasmid DNA (pDNA)-based gene therapy. Plasmids are extrachromosomal DNA capable of being transmitted from cell to cell. They are supercoiled, circular covalently closed (ccc) strands of DNA capable of replication independently of host DNA and ranging from 5 to 400 kilo base pairs (kb) in size, depending on the size of the therapeutic gene insert.
Description: This is the pre-peer reviewed version of the article which has been published in final form at: http://dx.doi.org/10.1002/bit.22581
Version: Submitted for publication
DOI: 10.1002/bit.22581
URI: https://dspace.lboro.ac.uk/2134/13370
Publisher Link: http://dx.doi.org/10.1002/bit.22581
ISSN: 0006-3592
Appears in Collections:Published Articles (Mechanical, Electrical and Manufacturing Engineering)

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