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|Title: ||A validated model of GAG deposition, cell distribution, and growth of tissue engineered cartilage cultured in a rotating bioreactor|
|Authors: ||Nikolaev, N.I.|
Versteeg, Henk K.
Williams, David J.
|Keywords: ||Mathematical model|
Cartilage tissue engineering
|Issue Date: ||2010|
|Publisher: ||© John Wiley and Sons|
|Citation: ||NIKOLAEV, N.I. ... et al, 2010. A validated model of GAG deposition, cell distribution, and growth of tissue engineered cartilage cultured in a rotating bioreactor. Biotechnology and Bioengineering, 105 (4), pp.842-853.|
|Abstract: ||The purpose of this article is to review the different strategies for the delivery of plasmid DNA (pDNA)-based gene therapy. Plasmids are extrachromosomal DNA capable of being transmitted from cell to cell. They are supercoiled, circular covalently closed (ccc) strands of DNA capable of replication independently of host DNA and ranging from 5 to 400 kilo base pairs (kb) in size, depending on the size of the therapeutic gene insert.|
|Description: ||This is the pre-peer reviewed version of the article which has been published in final form at: http://dx.doi.org/10.1002/bit.22581|
|Version: ||Submitted for publication|
|Publisher Link: ||http://dx.doi.org/10.1002/bit.22581|
|Appears in Collections:||Published Articles (Mechanical, Electrical and Manufacturing Engineering)|
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