The thesis illustrates the usefulness and importance of single
crystal X-Ray structure determinations in a number of systems.
Apart from gaining insight into molecular structures the technique
has been used to investigate a range of second order interactions
such as those involved in molecular receptors and those
responsible for the ordering of molecules in the solid state.
Twenty six papers incorporating over sixty crystal structures are
reproduced...[text continues]...A wide range of organic structural
problems are also described, from simple structural elucidations
to determinations of relative and absolute stereochemistries. The
exciting area of supramolecular chemistry is described in the final
four papers. Here, the overall conformation and packing of the
macrocycles, rotaxanes and catenanes is of interest;- the
conformation of cavities, a double helical mode (which obviously
has implications for molecules taken from nature) and the 'selfassembly'
of many of these systems to form large packing arrays
with many interactions is of primary importance. This area is of
interest for the development of sensors, molecular switches and
nanometer scale devices.
This thesis is closed access for copyright reasons. Publications submitted for the degree of Ph.D., Loughborough University, 1997.