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Title: The regioselective outcome of ring rearrangement metathesis transformations performed on bicyclo[2.2.2]oct-2-ene derivatives
Authors: Standen, Patricia E.
Kimber, Marc C.
Keywords: Bicyclic
Grignard
Ruthenium
Metathesis
Rearrangement
Issue Date: 2013
Publisher: © Elsevier Ltd
Citation: STANDEN, P.E. and KIMBER, M.C., 2013. The regioselective outcome of ring rearrangement metathesis transformations performed on bicyclo[2.2.2]oct-2-ene derivatives. Tetrahedron Letters, 54 (31), pp. 4098 - 4101
Abstract: Treatment of bicyclo[2.2.2]oct-2-en-7-one with organometallic reagents gives the addition products in good yield and moderate diastereoselectivities in favour of the syn-products. Subsequent exposure of these addition products to ruthenium catalysed ring rearrangement metathesis (RRM) conditions reveals significant product divergence as a consequence of the newly acquired stereocentre.
Description: This article was published in the journal, Tetrahedron Letters [© Elsevier Ltd]. The definitive version is available at: http://dx.doi.org/10.1016/j.tetlet.2013.05.112
Version: Accepted for publication
DOI: 10.1016/j.tetlet.2013.05.112
URI: https://dspace.lboro.ac.uk/2134/13933
Publisher Link: http://dx.doi.org/10.1016/j.tetlet.2013.05.112
ISSN: 0040-4039
Appears in Collections:Published Articles (Chemistry)

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