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Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/13949

Title: The selective mono and difunctionalization of carbocyclic cleft molecules with pyridyl groups and X-ray crystallographic analysis
Authors: Jilka, Priti
Millington, Claire
Elsegood, Mark R.J.
Frese, Josef W.A.
Teat, Simon J.
Kimber, Marc C.
Keywords: Carbocyclic cleft
Chiral cavity
Alkylation
Esterification
Recognition
Issue Date: 2010
Publisher: © Elsevier Ltd
Citation: JILKA, P. ... et al, 2010. The selective mono and difunctionalization of carbocyclic cleft molecules with pyridyl groups and X-ray crystallographic analysis. Tetrahedron, 66 (48), pp. 9327 - 9331
Abstract: The diesterification and selective mono and dialkylation of carbocyclic analogues of Tröger’s base with pyridyl groups has been achieved in high yield and good selectivity giving access to a novel range of cleft molecules capable of binding events. Reaction conditions for the selective functionalization of this carbocyclic cleft molecule are discussed as well as the solid state structures of these newly synthesized ligands.
Description: This article was published in the journal Tetrahedron [© Elsevier Ltd]. The definitive version is available at: http://dx.doi.org/10.1016/j.tet.2010.10.027
Version: Accepted for publication
DOI: 10.1016/j.tet.2010.10.027
URI: https://dspace.lboro.ac.uk/2134/13949
Publisher Link: http://dx.doi.org/10.1016/j.tet.2010.10.027
ISSN: 0040-4020
Appears in Collections:Published Articles (Chemistry)

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