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Title: A hybrid approach to determining cornea mechanical properties in vivo using a combination of nano-indentation and inverse finite element analysis
Authors: Abyaneh, M.H.
Wildman, Ricky D.
Ashcroft, Ian A.
Ruiz, Pablo D.
Keywords: Porcine cornea
Nano indentation
Stress relaxation
Inverse finite element method
Issue Date: 2013
Publisher: © Elsevier
Citation: ABYANEH, M.H. ... et al, 2013. A hybrid approach to determining cornea mechanical properties in vivo using a combination of nano-indentation and inverse finite element analysis. Journal of the Mechanical Behavior of Biomedical Materials, 27, pp. 239 - 248
Abstract: An analysis of the material properties of porcine corneas has been performed. A simple stress relaxation test was performed to determine the viscoelastic properties and a rheological model was built based on the Generalized Maxwell (GM) approach. A validation experiment using nano-indentation showed that an isotropic GM model was insufficient for describing the corneal material behaviour when exposed to a complex stress state. A new technique was proposed for determining the properties, using a combination of nano-indentation experiment, an isotropic and orthotropic GM model and inverse finite element method. The good agreement using this method suggests that this is a promising technique for measuring material properties in vivo and further work should focus on the reliability of the approach in practice.
Description: This article was published in the serial, Journal of the Mechanical Behavior of Biomedical Materials [© Elsevier]. The definitive version is available at: http://dx.doi.org/10.1016/j.jmbbm.2013.05.016
Version: Accepted for publication
DOI: 10.1016/j.jmbbm.2013.05.016
URI: https://dspace.lboro.ac.uk/2134/14035
Publisher Link: http://dx.doi.org/10.1016/j.jmbbm.2013.05.016
ISSN: 1751-6161
Appears in Collections:Published Articles (Mechanical, Electrical and Manufacturing Engineering)

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