A review of the discovery, biological properties, and synthesis
of the leukotrienes is presented. The opening of β-alkylstyrene
oxides with nucleophiles is also discussed, with respect to the
possible preparation of leukotriene analogues in which an aromatic
species replaces the triene system... cont'd
A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy of Loughborough University.