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Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/15128

Title: Effect of exercise on postprandial endothelial function in adolescent boys
Authors: Sedgwick, Matthew J.
Morris, John G.
Nevill, Mary
Tolfrey, Keith
Nevill, Alan
Barrett, Laura A.
Keywords: CHD risk
Flow-mediated dilation
Postprandial lipaemia
Issue Date: 2013
Publisher: Cambridge University Press on behalf of The Nutrition Society / © The Authors
Citation: SEDGWICK, M.J. ... et al, 2013. Effect of exercise on postprandial endothelial function in adolescent boys. British Journal of Nutrition, 110 (2), pp. 301 - 309.
Abstract: The ingestion of high-fat meals induces a state of endothelial dysfunction in adults. This dysfunction is attenuated by prior exercise. The response of young people to these nutritional and physiological stressors has not been established. Thus, the purpose of the present study was to investigate if a bout of moderate-intensity exercise influenced endothelial function (as indicated by flow-mediated dilation (FMD)) following the ingestion of a high-fat breakfast and lunch in adolescent boys (aged 12·6–14·3 years). Two, 2 d main trials (control and exercise) were completed by thirteen adolescent boys in a counter-balanced, cross-over design. Participants were inactive on day 1 of the control trial, but completed 60 min of walking at 60% peak oxygen uptake in the exercise trial. On day 2, endothelial function was assessed via FMD prior to, and following, ingestion of a high-fat breakfast and lunch. There was no difference in fasting FMD between the control and exercise trial (P¼0·449). In the control trial, FMD was reduced by 32% following consumption of the high-fat breakfast and by 24% following lunch. In the exercise trial, the corresponding reductions were 6 and 10 %, respectively (main effect trial, P¼0·002). These results demonstrate that moderate-intensity exercise can attenuate the decline in FMD seen following the consumption of high-fat meals in adolescent boys.
Description: This article was published in the serial, British Journal of Nutrition [Cambridge University Press on behalf of The Nutrition Society / © The Authors]. The article is also available at: http://journals.cambridge.org/action/displayJournal?jid=BJN
Version: Published
DOI: 10.1017/S0007114512004977
URI: https://dspace.lboro.ac.uk/2134/15128
Publisher Link: http://dx.doi.org/10.1017/S0007114512004977
ISSN: 0007-1145
Appears in Collections:Published Articles (Sport, Exercise and Health Sciences)

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