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Title: Cutaneous sensibility and peripheral nerve function in patients with unmedicated essential hypertension
Authors: Edwards, Louisa
Ring, Christopher
McIntyre, David
Winer, John B.
Martin, Una
Keywords: Cutaneous sensory thresholds
Essential hypertension
Median nerve
Nerve conduction velocity
Sensory action potential amplitudes
Issue Date: 2008
Publisher: Wiley / © Society for Psychophysiological Research
Citation: EDWARDS, L. ... et al, 2008. Cutaneous sensibility and peripheral nerve function in patients with unmedicated essential hypertension. Psychophysiology, 45 (1), pp. 141 - 147.
Abstract: Sensorimotor deficits in patients with essential hypertension may be due to impaired nerve function. Cutaneous sensory thresholds, median nerve sensory and motor conduction velocities, andmedian nerve sensory action potential amplitudes were assessed in 30 patients with unmedicated essential hypertension and 29 normotensives. Cutaneous sensory thresholds were higher and sensory action potential amplitudes smaller in hypertensives than normotensives whereas sensory and motor nerve conduction velocities did not differ between groups. These data suggest that hypertension may reduce the number of active sensory nerve fibers without affecting myelination. Sensory action potential amplitudes were inversely related to cutaneous sensory thresholds, suggesting that subclinical axonal neuropathy of sensory afferents may help account for perceptual deficits that characterize hypertension.
Description: This is the peer reviewed version of the following article: EDWARDS, L. ... et al, 2008. Cutaneous sensibility and peripheral nerve function in patients with unmedicated essential hypertension. Psychophsiology, 45 (1), pp. 141 - 147, which has been published in final form at: http://dx.doi.org/10.1111/j.1469-8986.2007.00608.x . This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.
Version: Accepted for publication
DOI: 10.1111/j.1469-8986.2007.00608.x
URI: https://dspace.lboro.ac.uk/2134/15380
Publisher Link: http://dx.doi.org/10.1111/j.1469-8986.2007.00608.x
ISSN: 0048-5772
Appears in Collections:Published Articles (Sport, Exercise and Health Sciences)

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