PsyP-2007-0113-R1manuscript.pdf (261.76 kB)
Cutaneous sensibility and peripheral nerve function in patients with unmedicated essential hypertension
journal contribution
posted on 2014-07-29, 13:03 authored by Louisa Edwards, Christopher Ring, David McIntyre, John B. Winer, Una MartinSensorimotor deficits in patients with essential hypertension may be due to impaired nerve function. Cutaneous
sensory thresholds, median nerve sensory and motor conduction velocities, andmedian nerve sensory action potential
amplitudes were assessed in 30 patients with unmedicated essential hypertension and 29 normotensives. Cutaneous
sensory thresholds were higher and sensory action potential amplitudes smaller in hypertensives than normotensives
whereas sensory and motor nerve conduction velocities did not differ between groups. These data suggest that
hypertension may reduce the number of active sensory nerve fibers without affecting myelination. Sensory action
potential amplitudes were inversely related to cutaneous sensory thresholds, suggesting that subclinical axonal neuropathy
of sensory afferents may help account for perceptual deficits that characterize hypertension.
History
School
- Sport, Exercise and Health Sciences
Published in
PSYCHOPHYSIOLOGYVolume
45Issue
1Pages
141 - 147 (7)Citation
EDWARDS, L. ... et al, 2008. Cutaneous sensibility and peripheral nerve function in patients with unmedicated essential hypertension. Psychophysiology, 45 (1), pp. 141 - 147.Publisher
Wiley / © Society for Psychophysiological ResearchVersion
- AM (Accepted Manuscript)
Publication date
2008Notes
This is the peer reviewed version of the following article: EDWARDS, L. ... et al, 2008. Cutaneous sensibility and peripheral nerve function in patients with unmedicated essential hypertension. Psychophsiology, 45 (1), pp. 141 - 147, which has been published in final form at: http://dx.doi.org/10.1111/j.1469-8986.2007.00608.x . This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.ISSN
0048-5772Publisher version
Language
- en