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|Title: ||One night's CPAP withdrawal in otherwise compliant OSA patients: marked driving impairment but good awareness of increased sleepiness|
|Authors: ||Filtness, Ashleigh J.|
Reyner, Louise A.
Horne, James A.
|Keywords: ||Driving performance|
Obstructive sleep apnoea
|Issue Date: ||2012|
|Publisher: ||© Springer-Verlag|
|Citation: ||FILTNESS, A.J., REYNER, L.A. and HORNE, J.A., 2012. One night's CPAP withdrawal in otherwise compliant OSA patients: marked driving impairment but good awareness of increased sleepiness. Sleep and Breathing, 16 (3), pp. 865-871.|
|Abstract: ||PURPOSE. OSA patients effectively treated by and compliant with CPAP occasionally miss a night’s
treatment. The purpose of this study was to use a real car interactive driving simulator to assess
the effects of such an occurrence on the next day’s driving, including the extent to which these
drivers are aware of increased sleepiness.
METHODS. 11 long-term compliant CPAP treated 50-75y male OSA participants completed a 2h
afternoon, simulated, realistic monotonous drive in an instrumented car, twice, following one night:
i) normal sleep with CPAP ii) nil CPAP. Drifting out of road lane (‘incidents’), subjective sleepiness
every 200sec and continuous EEG activities indicative of sleepiness and compensatory effort were
RESULTS. Withdrawal of CPAP markedly increased sleep disturbance, and led to significantly more
incidents, a shorter ‘safe’ driving duration, increased alpha and theta EEG power and greater
subjective sleepiness. However, increased EEG beta activity indicated more compensatory effort
was being applied. Importantly, under both conditions there was a highly significant correlation
between subjective and EEG measures of sleepiness, to the extent that participants were well
aware of the effects of nil CPAP. CONCLUSIONS. Patients should be aware that compliance with treatment every night is crucial for
|Description: ||The final publication is available at Springer via http://dx.doi.org/10.1007/s11325-011-0588-8.|
|Version: ||Submitted for publication|
|Publisher Link: ||http://dx.doi.org/10.1007/s11325-011-0588-8|
|Appears in Collections:||Published Articles (Sport, Exercise and Health Sciences)|
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