Loughborough University
Leicestershire, UK
LE11 3TU
+44 (0)1509 263171
Loughborough University

Loughborough University Institutional Repository

Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/15468

Title: Studies on the double alkylation of 2,2-disubstituted-1,3-dithiacycloalkane-S-oxides: synthesis of tertiary thiol derivatives
Authors: Fuchs, Christian
Edgar, Mark
Elsegood, Mark R.J.
Weaver, George W.
Issue Date: 2013
Publisher: © Royal Society of Chemistry
Citation: FUCHS, C. ... et al., 2013. Studies on the double alkylation of 2,2-disubstituted-1,3-dithiacycloalkane-S-oxides: synthesis of tertiary thiol derivatives. RSC Advances, 3, pp.21911-21918.
Abstract: Di-alkylation of 2,2-dimethyl-1,3-dithiacycloalkane-S-oxides has been achieved allowing the synthesis of two tertiary thiol centres. The diastereoisomers of the mono-alkylated products have been shown to react at different rates. The X-ray crystal structures of three substituted dithiane-S-oxides have been determined, and the conversion of the dialkylated products into cyclic disulfide derivatives of tertiary thiols (1,2-dithiolanes) has been achieved by treatment with acid.
Sponsor: The authors thank Loughborough University for financial support.
Version: Accepted for publication
DOI: 10.1039/c3ra43688h
URI: https://dspace.lboro.ac.uk/2134/15468
Publisher Link: http://dx.doi.org/10.1039/c3ra43688h
ISSN: 2046-2069
Appears in Collections:Published Articles (Chemistry)

Files associated with this item:

File Description SizeFormat
Christian Fuchs RSC Adv 20Aug13.pdfAccepted version375.64 kBAdobe PDFView/Open

 

SFX Query

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.