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Assessment of the feasibility of the use of conductive polymers in the fabrication of ion mobility spectrometers
journal contribution
posted on 2014-10-09, 10:06 authored by Theodoros Koimtzis, Nick J. Goddard, Ian D. Wilson, Paul ThomasThe development of an ion mobility spectrometer with an injection molded plastic drift tube made from carbon-loaded nylon and the cyclo-olefinpolymer Zeonex is described. Thermogravimetric assessment combined with headspace analysis by ion mobility spectrometry and gas chromatography−mass spectrometry indicated that Zeonex encapsulated carbon-loaded nylon could be used to fabricate a snap-together injection molded stacked ring drift tube, 4.25 cm long that could be substituted for a conventional wire-wound heated ceramic drift tube of the same length into a high temperature ion mobility spectrometer. Temperature stability experiments indicated that such a combination of polymers produced stable water-based reactant ion peaks [(H2O)nH]+ up to a temperature of approximately 50 °C. Above this temperature, ammonia appeared to outgas, resulting in the production of [(H2O)n(NH4)mH]+ type species before, at higher temperatures, the release of oligomeric entities suppressed resolved ion responses. Surface charging effects were also observed, and over a period of continuous operation of 4 h, these caused suppression of the signal intensity (1.11−0.954 V) and an apparent mobility shift in the observed responses (K0 = 1.86−1.90 cm2 V−1 s−1). Substituting nylon, a polymer with a significantly lower surface resistivity, for the Zeonex demonstrated how surface charging phenomena could be managed though control of surface resistivity in future polymer formulations. The device was challenged successfully with test atmospheres of hexan-1-ol (K0 = 1.66 cm2 V−1 s−1 (monomer) and 1.32 cm2 V−1 s−1(dimer)) and dimethylmethyl phosphonate (K0 = 1.70 cm2 V−1 s−1 (monomer) and 1.44 cm2 V−1 s−1 (dimer)). The potential advantages of developing polymeric systems using more advanced polymer formulations are discussed.
Funding
The work described in this paper was supported by a grant from AstraZeneca and took place as part of the National Initiative on Ion Mobility Spectrometry run at the former Department of Instrument and Analytical Science at UMIST and Nottingham Trent University with support from Waters Instruments, GlaxoSmithKline and AstraZeneca.
History
School
- Science
Department
- Chemistry
Published in
ANALYTICAL CHEMISTRYVolume
83Issue
7Pages
2613 - 2621 (9)Citation
KOIMTZIS, T. ... et al., 2011. Assessment of the feasibility of the use of conductive polymers in the fabrication of ion mobility spectrometers. Analytical Chemistry, 83 (7), pp. 2613 - 2621.Publisher
© American Chemical SocietyVersion
- AM (Accepted Manuscript)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2011Notes
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Analytical Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see: http://pubs.acs.org/doi/abs/10.1021/ac102997mISSN
0003-2700Publisher version
Language
- en