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Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/16452

Title: Structured biodegradable microparticles produced using glass microfluidic flow focussing devices
Authors: Ekanem, Ekanem E.
Vladisavljevic, Goran T.
Keywords: Microfluidic devices
Drug encapsulation
Biodegradable microparticles
Issue Date: 2014
Publisher: © Chemical and Biological Microsystems Society (CBMS)
Citation: EKANEM, E.E. and VLADISAVLJEVIC, G.T., 2014. Structured biodegradable microparticles produced using glass microfluidic flow focussing devices. IN: Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014), 26th-30th October 2014, San Antonio, Texas, USA. CBMS, pp. 971-973.
Abstract: Herein is reported the production of biodegradable poly (lactic acid) (PLA) and poly (lactic-co-glycolic acid) (PLGA) particles having modifiable internal and surface microstructures via single step emulsification using microfabricated 3D (axisymmetric) flow focusing glass capillary microfluidic devices and subsequent solvent evaporation. Controlled production of emulsion droplets was achieved and the morphology of particles produced after evaporation was investigated to ascertain its effect on hydrophobic drug encapsulation and release.
Description: This conference paper is closed access.
Version: Published
URI: https://dspace.lboro.ac.uk/2134/16452
Publisher Link: http://www.microtas2014.org/
ISBN: 978097980647
Appears in Collections:Closed Access (Chemical Engineering)

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