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From-production-to-patient-challenges-and-approaches-for-delivering-cell-therapies.pdf (3.91 MB)

From production to patient: challenges and approaches for delivering cell therapies.

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posted on 2015-02-23, 14:21 authored by Karen CoopmanKaren Coopman, Nick Medcalf
The cell therapy industry is rapidly growing with several new products approved for clinical use over the past few years and many more currently in clinical trials. Nonetheless, a number of challenges remain in getting cell therapies to the market and into routine use. For instance, cell therapy bioprocesses still need to be optimised, but if these therapies are to be widely adopted there must also be clear routes for their delivery from the site of manufacture to the clinic and the patients. This review explores the currently available routes, the factors that need to be taken into consideration when choosing a route and the challenges that remain with respect to cell therapy logistics.

Funding

The authors would like to acknowledge the Biotechnology and Biological Sciences Research Council (BBSRC; UK), Bioprocessing Research Industries Club (BRIC) and the Engineering and Physical Sciences Research Council (EPSRC; UK) for their financial support.

History

School

  • Aeronautical, Automotive, Chemical and Materials Engineering

Department

  • Chemical Engineering

Published in

StemBook [Internet]

Pages

N/A - N/A (N/A)

Citation

COOPMAN, K. and MEDCALF, N., 2014. From production to patient: challenges and approaches for delivering cell therapies. IN: Stem Cell Research Community (eds). StemBook, DOI:10.3824/stembook.1.97.1.

Publisher

StemBook / © The Authors

Version

  • VoR (Version of Record)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution 3.0 Unported (CC BY 3.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by/3.0/

Publication date

2014

Notes

This is an Open Access Book Chapter. It is published by StemBook under the Creative Commons Attribution 3.0 Licence. Full details of this licence are available at: http://creativecommons.org/licenses/by/3.0/

ISSN

1940-3429

Language

  • en

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