Final accepted manuscript (with figure 1).pdf (253.18 kB)
Salivary SIgA responses to acute moderate-vigorous exercise in monophasic oral contraceptive users
journal contribution
posted on 2015-04-08, 16:19 authored by Harumi Hayashida, Nicola J. Dolan, Charlotte Hounsome, Nawal Alajmi, Nicolette BishopNicolette BishopThe purpose of this study was to examine the effect of oral contraceptive (OC) use on salivary secretory immunoglobulin A (SIgA) levels at rest and in response to an acute bout of moderate-vigorous exercise during two phases of the 4 week OC cycle corresponding to different phases of the synthetic menstrual cycle. Ten healthy active females completed a cycling at 70% V(・)O2peak for 45 min at two time points of an OC cycle: during the equivalent in time to the mid-follicular phase (day 8 ± 2) and the mid-luteal phase (day 20 ± 2). Timed unstimulated saliva samples were obtained before, immediately post exercise and 1 h post exercise and analyzed for salivary SIgA. Salivary SIgA secretion rate was 26 % (95% Confidence limits, CI, 6-46) lower at post-exercise compared with pre-exercise during the synthetic follicular phase (p = 0.019) but no differences were observed during the synthetic luteal trial. Saliva flow rate was 11% (95% CI, 8-30) lower at post-exercise compared with pre-exercise (main effect for time; p = 0.025). In conclusion, the pattern of salivary SIgA secretion rate response to moderate-vigorous exercise varies across the early and late phases of a monophasic OC cycle, with a transient reduction in salivary SIgA responses during the synthetic follicular phase. These findings indicate that monophasic OC use should be considered when assessing mucosal immune responses to acute exercise.
History
School
- Sport, Exercise and Health Sciences
Published in
Applied Physiology, Nutrition, and MetabolismCitation
HAYASHIDA, H. ... et al, 2015. Salivary SIgA responses to acute moderate-vigorous exercise in monophasic oral contraceptive users. Applied Physiology, Nutrition, and Metabolism, 40(9), pp.863-867.Publisher
NRC Research Press / © The AuthorsVersion
- AM (Accepted Manuscript)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2015Notes
This article was published in the journal Applied Physiology, Nutrition, and Metabolism. The definitive version is available from: http://www.nrcresearchpress.com/journal/apnmISSN
1715-5320Publisher version
Language
- en