PAGE, P.C.B. ... et al, 2014. Carbohydrate-derived iminium salt organocatalysts for the asymmetric epoxidation of alkenes. Tetraheddron, 70 (40), pp.7283-7305
A new family of carbohydrate-based dihydroisoquinolinium salts has been prepared and tested for potential as asymmetric catalysts for the epoxidation of unfunctionalized alkene substrates, providing up to 57% ee in the product epoxides.
This is an Open Access Article. It is published by Elsevier as Open Access at: http://dx.doi.org/10.1016/j.tet.2014.07.052
This work was supported by Loughborough
University, the Engineering and Physical Sciences Research Council,
GlaxoSmithKline (CASE award), and The Royal Society (P.C.B.P.: Industry Fellowship).