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Title: Spatial variations in the microbial community structure and diversity of the human foot is associated with the production of odorous volatiles
Authors: Stevens, Deborah
Cornmell, Robert
Taylor, David
Grimshaw, Sally G.
Riazanskaia, Svetlana
Arnold, David S.
Fernstad, Sara J.
Smith, Adrian M.
Heaney, Liam M.
Reynolds, James C.
Thomas, C.L. Paul
Harker, Mark
Keywords: Isovaleric acid
Microbiomics
Odour
GC/MS
Issue Date: 2015
Publisher: Oxford University Press © FEMS
Citation: STEVENS, D. et al., 2015. Spatial variations in the microbial community structure and diversity of the human foot is associated with the production of odorous volatiles. FEMS Microbiology Ecology, 91 (1), pp. 1-11.
Abstract: The human foot provides an ideal environment for the colonization and growth of bacteria and subsequently is a body site associated with the liberation of odour. This study aimed to enumerate and spatially map bacterial populations’ resident across the foot to understand any association with odour production. Culture-based analysis confirmed that Staphylococci were present in higher numbers than aerobic corynebacteria and Gram-positive aerobic cocci, with all species being present at much higher levels on the plantar sites compared to dorsal sites. Microbiomic analysis supported these findings demonstrating that Staphylococcus spp. were dominant across different foot sites and comprised almost the entire bacterial population on the plantar surface. The levels of volatile fatty acids, including the key foot odour compound isovaleric acid, that contribute to foot odour were significantly increased at the plantar skin site compared to the dorsal surface. The fact that isovaleric acid was not detected on the dorsal surface but was present on the plantar surface is probably attributable to the high numbers of Staphylococcus spp. residing at this site. Variations in the spatial distribution of these microbes appear to be responsible for the localized production of odour across the foot.
Description: This is a pre-copyedited, author-produced PDF of an article accepted for publication in FEMS Microbiology Ecology following peer review. The version of record STEVENS, D. et al., 2015. Spatial variations in the microbial community structure and diversity of the human foot is associated with the production of odorous volatiles. FEMS Microbiology Ecology, 91 (1), pp. 1-11 is available online at: http://dx.doi.org/10.1093/femsec/fiu018
Version: Accepted for publication
DOI: 10.1093/femsec/fiu018
URI: https://dspace.lboro.ac.uk/2134/18359
Publisher Link: http://dx.doi.org/10.1093/femsec/fiu018
ISSN: 0168-6496
Appears in Collections:Published Articles (Chemistry)

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