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Title: Novel fabrication of hierarchically porous hydroxyapatite scaffolds with refined porosity and suitable strength
Authors: Chen, Z.C.
Zhang, X.L.
Zhou, Kui
Cai, H.
Liu, Changqing
Keywords: Hydroxyapatite scaffold
Hierarchical structure
Mechanical strength
Additional porosity
Issue Date: 2014
Publisher: © Institute of Materials, Minerals and Mining Published by Maney on behalf of the Institute
Citation: CHEN, Z.C. et al., 2014. Novel fabrication of hierarchically porous hydroxyapatite scaffolds with refined porosity and suitable strength. Advances in Applied Ceramics, 114 (3), pp. 183 - 187.
Abstract: Based on extrusion deposition and foaming technique, a novel method for biological hydroxyapatite (HA) scaffolds was introduced in this paper. The scaffolds were primarily characterised by interconnected and hierarchically porous structures with high porosity, adjustable distribution of pore sizes, as well as considerable mechanical strength. In order to confirm that fine control of bulk porosity and mechanical strength was possible and feasible, further analysis of obtained scaffolds was carried out by field emission scanning electron microscope (FESEM), compressive test and calculation of volumetric shrinkage; in particular, the additional porosity resulting from the introduction of pore former was evaluated. The results indicated that this method can have a great potential to construct HA scaffolds of suitable quality for spongy bone in bone tissue engineering.
Description: Closed access. This article was published in the journal, Advances in Applied Ceramics Volume 114 (3) and the definitive version is available at: http://www.maneyonline.com/doi/10.1179/1743676114Y.0000000213
Sponsor: Seventh European Community Framework Programme for financial support through a Marie Curie International Research Staff Exchange Scheme Project entitled ‘Micro-multi-material manufacture to enable multifunctional miniaturised devices (M6)’ (Grant No. PIRSESGA-2010-269113), as well as the Analytical and Testing Center in HUST.
Version: Published
DOI: 10.1179/1743676114Y.0000000213
URI: https://dspace.lboro.ac.uk/2134/18566
Publisher Link: http://dx.doi.org/10.1179/1743676114Y.0000000213
ISSN: 1743-6753
Appears in Collections:Closed Access (Mechanical, Electrical and Manufacturing Engineering)

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