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|Title: ||EuroTracker (R) dyes: design, synthesis, structure and photophysical properties of very bright europium complexes and their use in bioassays and cellular optical imaging|
|Authors: ||Butler, Stephen J.|
McMahon, Brian K.
Neil, Emily R.
Walton, James W.
Zwier, Jurriaan M.
|Issue Date: ||2015|
|Publisher: ||© The Royal Society of Chemistry|
|Citation: ||BUTLER, S.J. ... et al, 2015. EuroTracker (R) dyes: design, synthesis, structure and photophysical properties of very bright europium complexes and their use in bioassays and cellular optical imaging. Dalton Transactions, 44 (11), pp. 4791 - 4803.|
|Abstract: ||The development of the brightest luminescent europium(III) complexes is traced, including analysis of
the C3-symmetric core complex based on a functionalized triazacyclononane and identification of the
most suitable strongly absorbing chromophore. Strategies for the synthesis of the complexes, including
enantiopure analogues, are outlined and opportunities for applications in time-resolved microscopy and
spectral imaging emphasised. Practicable examples are introduced, including selective organelle staining
for cellular optical imaging at 65 nm resolution and the development of new bioassays using time resolved
|Description: ||This article was accepted for publication in the journal, Dalton Transactions [© Royal Society of Chemistry]. The definitive version is available at: http://dx.doi.org/10.1039/c4dt02785j|
|Sponsor: ||This work was supported by the ERC (SJB, ERN, RP, DP; FCC
266804), EC and EPSRC.|
|Version: ||Accepted for publication.|
|Publisher Link: ||http://dx.doi.org/10.1039/c4dt02785j|
|Appears in Collections:||Published Articles (Chemistry)|
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