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Title: Ratiometric detection of adenosine triphosphate (ATP) in water and real-time monitoring of apyrase activity with a tripodal zinc complex
Authors: Butler, Stephen J.
Keywords: Anions
ATP
Enzymes
Fluorescent probes
Quinolines
Issue Date: 2014
Publisher: © Wiley-VCH Verlag GmbH & Co.
Citation: BUTLER, S.J., 2014. Ratiometric detection of adenosine triphosphate (ATP) in water and real-time monitoring of apyrase activity with a tripodal zinc complex. Chemistry - A European Journal, 20 (48), pp. 15768 - 15774.
Abstract: Two tripodal fluorescent probes Zn⋅L1,2 have been synthesised, and their anion-binding capabilities were examined by using fluorescence spectroscopy. Probe Zn⋅L1 allows the selective and ratiometric detection of adenosine triphosphate (ATP) at physiological pH, even in the presence of several competing anions, such as ADP, phosphate and bicarbonate. The probe was applied to the real-time monitoring of the apyrase-catalysed hydrolysis of ATP, in a medium that mimics an extracellular fluid.
Description: This article is closed access.
Sponsor: S.J.B. wishes to thank the Ramsay Memorial Fellowship Trust and Durham University for support and funding.
Version: Published
DOI: 10.1002/chem.201404499
URI: https://dspace.lboro.ac.uk/2134/18774
Publisher Link: http://dx.doi.org/10.1002/chem.201404499
ISSN: 0947-6539
Appears in Collections:Closed Access (Chemistry)

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