Loughborough University
Leicestershire, UK
LE11 3TU
+44 (0)1509 263171
Loughborough University

Loughborough University Institutional Repository

Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/18878

Title: Atropo- and diastereoselective construction of tetracyclic biphenylazepinium salts derived from aminoalcohols: use as catalysts in enantioselective asymmetric epoxidation.
Authors: Page, Philip C. Bulman
Pearce, Christopher A.
Chan, Yohan
Parker, Phillip
Buckley, Benjamin R.
Rassias, Gerasimos A.
Elsegood, Mark R.J.
Issue Date: 2015
Publisher: © American Chemical Society
Citation: PAGE, P.C.B. ... et al, 2015. Atropo- and diastereoselective construction of tetracyclic biphenylazepinium salts derived from aminoalcohols: use as catalysts in enantioselective asymmetric epoxidation. Journal of Organic Chemistry, 80 (16), pp. 8036-8045.
Abstract: A range of new biphenylazepinium salt organocatalysts effective for asymmetric epoxidation has been developed incorporating an additional substituted oxazolidine ring, and providing improved enantiocontrol in alkene epoxidation over the parent structure. Starting from enantiomerically pure aminoalcohols, tetracyclic iminium salts were obtained as single diastereoisomers through an atroposelective oxazolidine formation
Description: This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Organic Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/acs.joc.5b01157
Sponsor: This investigation has enjoyed the support of Loughborough University, the EPSRC, the University of East Anglia, and the ERDF (ISCE-Chem & INTERREG IVa programme 4061). We are indebted to the Royal Society for an Industry Fellowship (to PCBP) and the EPSRC national mass spectrometry service at the University of Wales, Swansea.
Version: Accepted for publication
DOI: 10.1021/acs.joc.5b01157
URI: https://dspace.lboro.ac.uk/2134/18878
Publisher Link: http://dx.doi.org/10.1021/acs.joc.5b01157
ISSN: 1520-6904
Appears in Collections:Published Articles (Chemistry)

Files associated with this item:

File Description SizeFormat
Oxazolidine 16-07-15 JOC.pdfAccepted version338.84 kBAdobe PDFView/Open

 

SFX Query

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.