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|Title: ||The effects of high-intensity interval training on glucose regulation and insulin resistance: a meta-analysis|
|Authors: ||Jelleyman, C.|
King, James A.
Davies, Melanie J.
|Issue Date: ||2015|
|Publisher: ||© Wiley|
|Citation: ||JELLEYMAN, C. ...et al., 2015. The effects of high-intensity interval training on glucose regulation and insulin resistance: a meta-analysis. Obesity Reviews, 16(11), pp.942–961.|
|Abstract: ||The aim of this meta-analysis was to quantify the effects of high-intensity interval training (HIIT) on markers of glucose regulation and insulin resistance compared to control conditions (CON) or continuous training (CT). Databases were searched for HIIT interventions based on the inclusion criteria: training ≥2 weeks, adult participants, and outcome measurements that included insulin resistance, fasting glucose, HbA1c or fasting insulin. Dual interventions and participants with type 1 diabetes were excluded. Fifty studies were included. There was a reduction in insulin resistance following HIIT compared to both CON & CT, (HIIT vs. CON: standardised mean difference (SMD)=-0.49, confidence intervals (CI) -0.87 to -0.12, p=0.009; CT: SMD=-0.35, -0.68 to -0.02, p=0.036). Compared to CON, HbA1c decreased by 0.19% (-0.36 to -0.03, p=0.021) and body weight decreased by 1.3kg (-1.9 to -0.7, p<0.001). There were no statistically significant differences between groups in other outcomes overall. However, participants with or at risk of Type 2 diabetes experienced reductions in fasting glucose (-0.92mmol.L-1, -1.22 to -0.62, p<0.001) compared to CON. HIIT appears effective at improving metabolic health, particularly in those at risk of or with Type 2 diabetes. Larger randomised controlled trials of longer duration than those included in this meta-analysis are required to confirm these results|
|Description: ||This article is in Closed Access until 20th Oct 2016.|
|Version: ||Accepted for publication|
|Publisher Link: ||http://dx.doi.org/10.1111/obr.12317|
|Appears in Collections:||Closed Access (Sport, Exercise and Health Sciences)|
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