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Title: Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
Authors: Hamer, Mark
von Kanel, Roland
Reimann, Manja
Malan, Nico T.
Schutte, Alta E.
Huisman, Hugo W.
Malan, Leone
Keywords: Black African
Cardiovascular disease
Issue Date: 2014
Publisher: © The Authors. Published by Elsevier Ireland Ltd.
Citation: HAMER, M. ... et al., 2014. Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study. Atherosclerosis, 238 (1), pp. 52–54.
Abstract: Recent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD) among urban black South Africans. The aim was to track the progression of CVD risk factors in a multiethnic sample of South Africans. Participants were 173 black (aged 47.5 ± 7.8 yrs) and 186 white teachers (aged 49.6 ± 9.9 yrs) that were examined at baseline and 3 years follow-up. Blacks demonstrated a substantially higher prevalence of composite CVD burden (defined as history of physician diagnosed heart disease, use of anti-hypertensives, anti-diabetic, or statin medications at either time point) compared to whites (49.1 vs. 32.0%, p ¼ 0.012) respectively. After controlling for baseline, the black participants demonstrated greater increases in 24 h systolic and diastolic blood pressure, total cholesterol, fasting glucose, fibrinogen, D-dimer, and waist circumference in comparison with whites. In summary, an adverse progression of CVD risk factors was observed in the whole sample, although to a larger degree in black participants. Aggressive treatment strategies for controlling risk factors in black Africans are needed to reduce the increasing burden of CVD in South Africa.
Description: This is an open access article under the CC BY-NC-SA license (http://creativecommons.org/licenses/by-ncsa/3.0/).
Sponsor: The study was partly funded by The Metabolic Syndrome Institute, France; the Medical Research Council, National Research Foundation, North-West University, and North-West Department of Education, South Africa. MH is supported by the British Heart Foundation (RE/10/005/28296).
Version: Published
DOI: 10.1016/j.atherosclerosis.2014.11.019
URI: https://dspace.lboro.ac.uk/2134/19175
Publisher Link: http://dx.doi.org/10.1016/j.atherosclerosis.2014.11.019
ISSN: 1879-1484
Appears in Collections:Published Articles (Sport, Exercise and Health Sciences)

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