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Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/19222

Title: Are sitting occupations associated with increased all-cause, cancer, and cardiovascular disease mortality risk? A pooled analysis of seven British population cohorts
Authors: Stamatakis, Emmanuel
Chau, Josephine Y.
Pedisic, Zeljko
Bauman, Adrian
Macniven, Rona
Coombs, Ngaire A.
Hamer, Mark
Issue Date: 2013
Publisher: © The Authors. Published by Public Library of Science
Citation: STAMATAKIS, E. ... et al., 2013. Are sitting occupations associated with increased all-cause, cancer, and cardiovascular disease mortality risk? A pooled analysis of seven British population cohorts.. PLoS One, 8(9): e73753.
Abstract: Background: There is mounting evidence for associations between sedentary behaviours and adverse health outcomes, although the data on occupational sitting and mortality risk remain equivocal. The aim of this study was to determine the association between occupational sitting and cardiovascular, cancer and all-cause mortality in a pooled sample of seven British general population cohorts. Methods: The sample comprised 5380 women and 5788 men in employment who were drawn from five Health Survey for England and two Scottish Health Survey cohorts. Participants were classified as reporting standing, walking or sitting in their work time and followed up over 12.9 years for mortality. Data were modelled using Cox proportional hazard regression adjusted for age, waist circumference, self-reported general health, frequency of alcohol intake, cigarette smoking, nonoccupational physical activity, prevalent cardiovascular disease and cancer at baseline, psychological health, social class, and education. Results: In total there were 754 all-cause deaths. In women, a standing/walking occupation was associated with lower risk of all-cause (fully adjusted hazard ratio [HR] = 0.68, 95% CI 0.52–0.89) and cancer (HR = 0.60, 95% CI 0.43–0.85) mortality, compared to sitting occupations. There were no associations in men. In analyses with combined occupational type and leisure-time physical activity, the risk of all-cause mortality was lowest in participants with non-sitting occupations and high leisure-time activity. Conclusions: Sitting occupations are linked to increased risk for all-cause and cancer mortality in women only, but no such associations exist for cardiovascular mortality in men or women.
Description: This is an Open Access Article. It is published by Public Library of Science under the Creative Commons Attribution 4.0 Unported Licence (CC BY). Full details of this licence are available at: http://creativecommons.org/licenses/by/4.0/
Version: Published
DOI: 10.1371/journal.pone.0073753
URI: https://dspace.lboro.ac.uk/2134/19222
Publisher Link: http://dx.doi.org/10.1371/journal.pone.0073753
ISSN: 1932-6203
Appears in Collections:Published Articles (Sport, Exercise and Health Sciences)

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