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Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/20249

Title: The role of light in measuring ocular biomechanics
Authors: Wilson, Abby
Marshall, J.
Tyrer, John R.
Issue Date: 2016
Publisher: © Nature Publishing Group on behalf of the Royal College of Ophthalmologists
Citation: WILSON, A., MARSHALL, J. and TYRER, J.R., 2016. The role of light in measuring ocular biomechanics. Eye, 30( 2), pp.234-040.
Abstract: The cornea is a highly specialised tissue with a unique set of biomechanical properties determined by its complex structure. The maintenance of these mechanical properties is fundamental to maintain clear vision as the cornea provides the majority of the focussing power of the eye. Changes to the biomechanics of the cornea can occur during ageing, disease, and trauma, or as a result of surgery. Recently there has been increased interest in the mechanical properties of the cornea as knowledge of these properties has significant implications for the improvement of current ocular treatments including PRK and LASIK, and for the diagnosis and tracking of corneal diseases and therapy such as keratoconus and crosslinking. Biomechanics are also important for the development of artificial corneal replacements. This paper describes the use of a novel, non-destructive lateral electronic speckle pattern shearing interferometer (ESPSI). The data generated via this technique give a full-field view of the mechanical response of the cornea under simulated physiological loading conditions, and enables strain and displacement to be determined in three planes. The technique allows corneal stiffness to be quantified and enables changes and non-homogeneities that occur due to surgery or disease to be detected.Eye advance online publication, 15 January 2016; doi:10.1038/eye.2015.263.
Description: This paper was accepted for publication in the journal Eye and the definitive published version is available at http://dx.doi.org/10.1038/eye.2015.263
Version: Accepted for publication
DOI: 10.1038/eye.2015.263
URI: https://dspace.lboro.ac.uk/2134/20249
Publisher Link: http://dx.doi.org/10.1038/eye.2015.263
ISSN: 0950-222X
Appears in Collections:Published Articles (Mechanical, Electrical and Manufacturing Engineering)

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