Loughborough University
Leicestershire, UK
LE11 3TU
+44 (0)1509 263171
Loughborough University

Loughborough University Institutional Repository

Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/20506

Title: Effect of a high and low dose of caffeine on human lymphocyte activation in response to antigen stimulation
Authors: Dulson, Deborah K.
Bishop, Nicolette
Keywords: Caffeine
T cell
NK cell
Issue Date: 2016
Publisher: NRC Research Press
Citation: DULSON, D.K. and BISHOP, N., 2016. Effect of a high and low dose of caffeine on human lymphocyte activation in response to antigen stimulation. Applied Physiology Nutrition and Metabolism, 41 (2), pp. 224 - 227.
Abstract: This study investigated the effect of caffeine on antigen-stimulated lymphocyte activation. Six males rested for 3.5 h after ingesting 0 (PLA), 2, or 6 (6CAF) mg·kg−1 body mass of caffeine. The number of antigen-stimulated NK CD69+ cells increased in 6CAF at 1 h compared with PLA (P = 0.021). Caffeine did not influence the number of antigen-stimulated CD69+ T cells or the geometric mean fluorescence intensity expression of CD69 on antigen-stimulated lymphocytes, suggesting caffeine has little effect on antigen-stimulated lymphocyte activation.
Description: This is the accepted version of an article subsequently published in the journal, Applied Physiology, Nutrition, and Metabolism. The definitive version is available at: http://dx.doi.org/10.1139/apnm-2015-0456.
Version: Accepted for publication
DOI: 10.1139/apnm-2015-0456
URI: https://dspace.lboro.ac.uk/2134/20506
Publisher Link: http://dx.doi.org/10.1139/apnm-2015-0456
ISSN: 1715-5312
Appears in Collections:Published Articles (Sport, Exercise and Health Sciences)

Files associated with this item:

File Description SizeFormat
ACCEPTED with Figure Dulson Bishop APNM 2016.pdfAccepted version230.02 kBAdobe PDFView/Open


SFX Query

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.