+44 (0)1509 263171
Please use this identifier to cite or link to this item:
|Title: ||Low-cost and effective fabrication of biocompatible nanofibers from silk and cellulose-rich materials|
|Authors: ||Guzman-Puyol, Susana|
Heredia-Guerrero, Jose A.
Bayer, Ilker S.
|Issue Date: ||2016|
|Publisher: ||© American Chemical Society|
|Citation: ||GUZMAN-PUYOL, S. ...et al., 2016. Low-cost and effective fabrication of biocompatible nanofibers from silk and cellulose-rich materials. ACS Biomaterials Science & Engineering, In Press.|
|Abstract: ||Here, we show the production of nanofibrous mats with controlled mechanical properties and excellent biocompatibility by combining fibroin with pure cellulose and cellulose-rich parsley powder agro-waste. To this end, trifluoroacetic acid was used as a common solvent for all of the involved biomaterials, achieving highly homogeneous blends that were suitable for the electrospinning technique. Morphological analysis revealed that the electrospun composite nanofibers were well-defined and defect-free, with a diameter in the range of 65−100 nm. Mechanical investigations demonstrated that the fibrous mats exhibited an increased stiffness when pure fibroin was combined with cellulose, whereas they possessed an increased flexibility when the parsley waste was added to fibroin. Lastly, the produced mats were highly biocompatible, as demonstrated by the promoted proliferation of fibroblast cells. The characteristics of the hybrid fibroin−cellulose nanofibers, in terms of nanoscale topography, mechanical properties, and biocompatibility, are attractive and potentially applicable in the biomedical sector.|
|Description: ||This paper is in closed access.|
|Version: ||Accepted for publication|
|Publisher Link: ||http://dx.doi.org/10.1021/acsbiomaterials.5b00500|
|Appears in Collections:||Closed Access (Materials)|
Files associated with this item:
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.