Loughborough University
Leicestershire, UK
LE11 3TU
+44 (0)1509 263171
Loughborough University

Loughborough University Institutional Repository

Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/21739

Title: Engineering design of artificial vascular junctions for 3D printing
Authors: Han, Xiaoxiao
Bibb, Richard J.
Harris, Russell A.
Keywords: Vascular vessel design
Computational fluid dynamics (CFD)
Additive manufacturing
3D printing
Issue Date: 2016
Publisher: © IOP Publishing
Citation: HAN, X., BIBB, R.J. and HARRIS, R.A., 2016. Engineering design of artificial vascular junctions for 3D printing. Biofabrication, 8, 025018.
Abstract: Vascular vessels, including arteries, veins and capillaries, are being printed using additive manufacturing technologies, also known as 3D printing. This paper demonstrates that it is important to follow the vascular design by nature as close as possible when 3D printing artificial vascular branches. In previous work, the authors developed an algorithm of computational geometry for constructing smooth junctions for 3D printing. In this work, computational fluid dynamics (CFDs) is used to compare the wall shear stress and blood velocity field for the junctions of different designs. The CFD model can reproduce the expected wall shear stress at locations remote from the junction. For large vessels such as veins, it is shown that ensuring the smoothness of the junction and using smaller joining angles as observed in nature is very important to avoid high wall shear stress and recirculation. The issue is however less significant for capillaries. Large joining angles make no difference to the hemodynamic behavior, which is also consistent with the fact that most capillary junctions have large joining angles. The combination of the CFD analysis and the junction construction method form a complete design method for artificial vascular vessels that can be 3D printed using additive manufacturing technologies.
Description: This is an author-created, un-copyedited version of an article accepted for publication/published in Biofabrication. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at http://dx.doi.org/10.1088/1758-5090/8/2/025018
Sponsor: This work was financially supported by the Eur opean Union’s Seventh Framework Programme (FP/ 2007-2013) under grant agreement No. 263416 (ArtiVasc 3D).
Version: Accepted for publication
DOI: 10.1088/1758-5090/8/2/025018
URI: https://dspace.lboro.ac.uk/2134/21739
Publisher Link: http://dx.doi.org/10.1088/1758-5090/8/2/025018
ISSN: 1758-5090
Appears in Collections:Published Articles (Mechanical, Electrical and Manufacturing Engineering)
Published Articles (Design School)

Files associated with this item:

File Description SizeFormat
Han_Manuscript__Biofabrication_RV4.pdfAccepted version1.17 MBAdobe PDFView/Open


SFX Query

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.