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Title: Complex character analysis of heart rate variability following brain asphyxia
Authors: Cai, Yuanyuan
Qiu, Yihong
Wei, Lan
Zhang, Wei
Hu, Sijung
Smith, Peter R.
Crabtree, Vincent P.
Tong, Shanbao
Thakor, Nitish V.
Zhu, Yisheng
Keywords: Brain asphyxia
Heart rate variability
Renyi entropy
L–Z complexity
Issue Date: 2006
Publisher: © Elsevier
Citation: CAI, Y. ... et al., 2006. Complex character analysis of heart rate variability following brain asphyxia. Medical Engineering and Physics, 28 (4), pp.297-303.
Abstract: In the present study Renyi entropy and L–Z complexity were used to characterize heart rate variability (HRV) of rats that were suffered from brain asphyxia and ischemia. Two groups of rats were studied: (a) rats (n = 5) injected with NAALADase inhibitor, 2-PMPA, which has been proven neuroprotective in asphyxia injury and (b) control subjects (n = 5) without medication. Renyi entropy and L–Z complexity of the R–R intervals (RRI) at different experiment stages were investigated in the two groups. The results show that both measures indicate less injury and better recovery in the drug injection group. The dynamic change of 90 min RRI signal after the asphyxia was investigated. The sudden reduction of the two parameters shows their sensitivity to the asphyxia insult.
Description: Closed access.
Sponsor: This research is supported by the grant 60272326 of National Natural Science Foundation of China and the 973 grant 2005CB7243 of National Natural Science Foundation of China.
Version: Published
DOI: 10.1016/j.medengphy.2005.05.002
URI: https://dspace.lboro.ac.uk/2134/22226
Publisher Link: http://dx.doi.org/10.1016/j.medengphy.2005.05.002
ISSN: 1350-4533
Appears in Collections:Closed Access (Mechanical, Electrical and Manufacturing Engineering)

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