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|Title: ||Healthy obesity as an intermediate state of risk: A critical review|
|Authors: ||Bell, Joshua A.|
Body mass index
Type 2 diabetes
|Issue Date: ||2016|
|Publisher: ||© Expert Reviews. Published by Taylor and Francis|
|Citation: ||BELL, J.A. and HAMER, M., 2016. Healthy obesity as an intermediate state of risk: A critical review. Expert Review of Endocrinology and Metabolism, 11 (5), pp. 403-413.|
|Abstract: ||Introduction: Obesity is a top public health priority but interventions to reverse the condition have had limited success. About 1-in-3 obese adults are free of metabolic risk factor clustering and are considered ‘healthy', and much attention has focused on the implications of this state for obesity management.
Areas covered: We searched for individual studies, systematic reviews, and meta-analyses which examined correlates and outcomes of metabolically healthy obesity. We discuss the key roles of fat distribution and physical activity in determining healthy vs. unhealthy obesity and report a greatly increased risk of incident type 2 diabetes associated with healthy obesity vs. healthy normal-weight, among other outcomes. We argue that despite inconsistencies in the definition, patterns across studies clearly show that healthy obesity is a state of intermediate disease risk.
Expert commentary: Given the current state of population-level evidence, we conclude that obesity and metabolic dysfunction are inseparable and that healthy obesity is best viewed only as a state of relative health but not of absolute health. We recommend that weight loss through energy restriction be a stand-alone target in addition to increased physical activity for minimising risk of future disease.|
|Description: ||This is an Accepted Manuscript of an article published by Taylor & Francis in Expert Review of Endocrinology and Metabolism on 12 Aug 2016, available online: http://dx.doi.org/10.1080/17446651.2016.1220298|
|Version: ||Accepted for publication|
|Publisher Link: ||http://dx.doi.org/10.1080/17446651.2016.1220298|
|Appears in Collections:||Published Articles (Sport, Exercise and Health Sciences)|
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