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Title: Healthy obesity as an intermediate state of risk: A critical review
Authors: Bell, Joshua A.
Hamer, Mark
Keywords: Obesity
Body mass index
Metabolic health
Physical activity
Cardiorespiratory fitness
Type 2 diabetes
Cardiovascular disease
Issue Date: 2016
Publisher: © Expert Reviews. Published by Taylor and Francis
Citation: BELL, J.A. and HAMER, M., 2016. Healthy obesity as an intermediate state of risk: A critical review. Expert Review of Endocrinology and Metabolism, 11 (5), pp. 403-413.
Abstract: Introduction: Obesity is a top public health priority but interventions to reverse the condition have had limited success. About 1-in-3 obese adults are free of metabolic risk factor clustering and are considered ‘healthy', and much attention has focused on the implications of this state for obesity management. Areas covered: We searched for individual studies, systematic reviews, and meta-analyses which examined correlates and outcomes of metabolically healthy obesity. We discuss the key roles of fat distribution and physical activity in determining healthy vs. unhealthy obesity and report a greatly increased risk of incident type 2 diabetes associated with healthy obesity vs. healthy normal-weight, among other outcomes. We argue that despite inconsistencies in the definition, patterns across studies clearly show that healthy obesity is a state of intermediate disease risk. Expert commentary: Given the current state of population-level evidence, we conclude that obesity and metabolic dysfunction are inseparable and that healthy obesity is best viewed only as a state of relative health but not of absolute health. We recommend that weight loss through energy restriction be a stand-alone target in addition to increased physical activity for minimising risk of future disease.
Description: This is an Accepted Manuscript of an article published by Taylor & Francis in Expert Review of Endocrinology and Metabolism on 12 Aug 2016, available online: http://dx.doi.org/10.1080/17446651.2016.1220298
Version: Accepted for publication
DOI: 10.1080/17446651.2016.1220298
URI: https://dspace.lboro.ac.uk/2134/22265
Publisher Link: http://dx.doi.org/10.1080/17446651.2016.1220298
ISSN: 1744-6651
Appears in Collections:Published Articles (Sport, Exercise and Health Sciences)

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