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|Title: ||Morphological and biological characterization of density-engineered foams fabricated by ultrasonic sonication|
|Authors: ||Torres-Sánchez, Carmen|
Corney, Jonathan R.
|Issue Date: ||2011|
|Publisher: ||© Springer|
|Citation: ||TORRES-SANCHEZ, C. and CORNEY, J., 2011. Morphological and biological characterization of density-engineered foams fabricated by ultrasonic sonication. Journal of Materials Science, 46 (2), pp.490-499.|
|Abstract: ||The successful manufacture of functionally tailored materials (e.g., density engineered foams) for advanced applications (e.g., structures or in bioengineering) requires an effective control over the process variables. In order to achieve this, density gradation needs to be represented and quantified. Current density measurement techniques offer information on bulk values, but neglect local position as valuable information (i.e., do not associate density scalar values with specific location, which is frequently critical when mechanical properties or functionalities have to be engineered). In this article, we present a method that characterizes the density gradation of engineered foams manufactured by the sonication technique, which allows the generation of sophisticated porous architectures beyond a simple linear gradient. A 3D data capture (μCT) and a flexible analysis software program (ImageJ) are used to obtain "global" density gradation values that can, ultimately, inform, control, and optimize the manufacture process. Polymeric foams, i.e., polyurethane (PU) foams, were used in this study as proof of concept. The measurements performed on the PU foams were validated by checking consistency in the results for both horizontal and vertical image slices. Biological characterization was done to assess the samples' tailored structure viability as scaffolds for tissue engineering. The comparison between untreated and sonicated samples yielded a 12.7% of increment in living cell count adhered to the walls after treatment. The conclusions drawn from this study may inform the design and manufacture of density-engineered materials used in other fields (e.g., structural materials, optoelectronics, food technology, etc.)|
|Version: ||Accepted for publication|
|Publisher Link: ||http://dx.doi.org/10.1007/s10853-010-4944-z|
|Appears in Collections:||Published Articles (Mechanical, Electrical and Manufacturing Engineering)|
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