pH responsive chiral nanostructures.pdf (734.17 kB)
pH-responsive chiral nanostructures
journal contribution
posted on 2016-10-17, 13:17 authored by Jianzhong Du, Helen WillcockHelen Willcock, Nga Sze Ieong, Rachel K. O'ReillyThere is great current interest in the design of robust synthetic polymers for the preparation of novel functional, well-defined, biocompatible and tailorable materials for a range of possible applications. In this work we have used reversible addition fragmentation chain transfer (RAFT) polymerization to prepare chiral and responsive amphiphilic block copolymers (based on polyphenylalanine acrylamide), which can be assembled at different pHs to form well-defined nanostructures. The morphology and size of the derived block polymers were explored using TEM, DLS and SLS measurements, while stability was examined by fluorescence and NMR spectroscopy. The application of these chiral and responsive nanostructures in the resolution of hydrophilic racemic amino acids has also been explored.
Funding
The authors thank the EPSRC, the Royal Society, the Leverhulme Trust and the University of Warwick for funding. Some of the equipment used in this research was ... part-funded by the European Regional Development Fund (ERDF).
History
School
- Aeronautical, Automotive, Chemical and Materials Engineering
Department
- Materials
Published in
Australian Journal of ChemistryVolume
64Issue
8Pages
1041 - 1046Citation
DU, J. ... et al., 2011. pH-responsive chiral nanostructures. Australian Journal of Chemistry, 64 (8), pp.1041-1046.Publisher
© CSIROVersion
- AM (Accepted Manuscript)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Publication date
2011ISSN
0004-9425eISSN
1445-0038Publisher version
Language
- en