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Title: Short-term outcome of treatment limitation discussions for newborn infants, a multicentre prospective observational cohort study
Authors: Aladangady, Narendra
Shaw, Chloe
Gallagher, Katie
Stokoe, Elizabeth
Marlow, Neil
Issue Date: 2017
Publisher: © The authors. Published by the BMJ Publishing Group
Citation: ALADANGADY, N. 2017. Short-term outcome of treatment limitation discussions for newborn infants, a multicentre prospective observational cohort study. Archives of Disease in Childhood: Fetal and Neonatal Edition, 102(2): F104-F109.
Abstract: Objective To determine the short-term outcomes of babies for whom clinicians or parents discussed the limitation of life-sustaining treatment (LST). Design Prospective multicentre observational study. Setting Two level 3, six level 2 and one level 1 neonatal units in the North-East London Neonatal Network. Participants A total of 87 babies including 68 for whom limiting LST was discussed with parents and 19 babies died without discussion of limiting LST in the labour ward or neonatal unit. Outcome measures Final decision reached after discussions about limiting LST and neonatal unit outcomes (death or survived to discharge) for babies. Results Withdrawing LST, withholding LST and do not resuscitate (DNR) order was discussed with 48, 16 and 4 parents, respectively. In 49/68 (72%) cases decisions occurred in level 3 and 19 cases in level 2 units. Following the initial discussions, 34/68 parents made the decision to continue LST. In 33/68 cases, a second opinion was obtained. The parents of 14/48 and 2/16 babies did not agree to withdraw and withhold LST, respectively. Forty-seven out of 87 babies (54%) died following limitation of LST, 28/87 (32%) died receiving full intensive care support, 5/87 (6%) survived following a decision to limit LST and 7/87 (8%) babies survived following decision to continue LST. Conclusions A significant proportion of parents chose to continue treatment following discussions regarding limiting LST for their babies, and a proportion of these babies survived to neonatal unit discharge. The long-term outcomes of babies who survive following limiting LST discussion need to be investigated.
Description: This paper was accepted for publication in the journal Archives of Disease in Childhood: Fetal and Neonatal Edition and the definitive published version is available at http://dx.doi.org/10.1136/archdischild-2016-310723
Sponsor: The National Institute for Health Research (NIHR) funded the study (RP-DG-0611-10006).
Version: Accepted for publication
DOI: 10.1136/archdischild-2016-310723
URI: https://dspace.lboro.ac.uk/2134/23437
Publisher Link: http://dx.doi.org/10.1136/archdischild-2016-310723
ISSN: 1468-2052
Appears in Collections:Published Articles (Social Sciences)

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