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Title: Noncontact blood perfusion mapping in clinical applications
Authors: Iakovlev, Dmitry
Dwyer, Vincent M.
Hu, Sijung
Silberschmidt, Vadim V.
Issue Date: 2016
Publisher: © SPIE
Citation: IAKOVLEV, D. ... et al, 2016. Noncontact blood perfusion mapping in clinical applications. IN: Popp, J. ... et al (eds). Biophotonics: Photonic Solutions for Better Health Care V, 988712 (April 27, 2016), Proceedings of SPIE, 9887, doi:10.1117/12.2225216
Abstract: © 2016 SPIE.Non-contact imaging photoplethysmography (iPPG) to detect pulsatile blood microcirculation in tissue has been selected as a successor to low spatial resolution and slow scanning blood perfusion techniques currently employed by clinicians. The proposed iPPG system employs a novel illumination source constructed of multiple high power LEDs with narrow spectral emission, which are temporally modulated and synchronised with a high performance sCMOS sensor. To ensure spectrum stability and prevent thermal wavelength drift due to junction temperature variations, each LED features a custom-designed thermal management system to effectively dissipate generated heat and auto-adjust current flow. The use of a multi-wavelength approach has resulted in simultaneous microvascular perfusion monitoring at various tissue depths, which is an added benefit for specific clinical applications. A synchronous detection algorithm to extract weak photoplethysmographic pulse-waveforms demonstrated robustness and high efficiency when applied to even small regions of 5 mm2. The experimental results showed evidences that the proposed system could achieve noticeable accuracy in blood perfusion monitoring by creating complex amplitude and phase maps for the tissue under examination.
Description: Copyright © 2016 SPIE. Society of Photo Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Version: Published
DOI: 10.1117/12.2225216
URI: https://dspace.lboro.ac.uk/2134/23661
Publisher Link: http://dx.doi.org/10.1117/12.2225216
ISBN: 9781510601321
ISSN: 0277-786X
Appears in Collections:Published Articles (Mechanical, Electrical and Manufacturing Engineering)

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