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Title: MgO implanted in rat tibia bone marrow is osteoinductive through the formation of a matrix, containing hydroxyapatite
Authors: Nygren, Hakan
Malmberg, Per
Liu, Yang
Keywords: Bone cement
Bone healing
Hydroxyl-apatite
Magnesium
Issue Date: 2016
Publisher: © Trans Tech Publications
Citation: NYGREN, H., MALMBERG, P. and LIU, Y., 2016. MgO implanted in rat tibia bone marrow is osteoinductive through the formation of a matrix, containing hydroxyapatite. IN: Sommitsch, C. ... et al. (eds). THERMEC 2016, 9th International Conference on Processing & Manufacturing of Advanced Materials, Graz, Austria, 29th May - 3rd June 2016. Trans Tech Publications, pp. 1404-1407.
Series/Report no.: Materials Science Forum;879
Abstract: Healing of rat tibia after intramedullary implantation of MgO was analysed by Environmental Scanning Electron Microscopy (ESEM) and Energy-Dispersive X-ray spectroscopy (EDX). The results indicated the formation of hydroxyl-apatite (HA) in the entire intramedullary space after 1 week of healing. Then, corroded Mg, MgO and MgCO3 were incubated with DMEM in vitro for 24 h and the surface of the material was analysed by EDX and Time-of-Flight Secondary Ion Mass (ToF-SIMS). The chemical analysis of the Mg corrosion products indicate that HA is formed at the material surface and that MgCO3 was an efficient catalyzer of HA formation.
Description: This is a conference paper. It was published in the series Materials Science Forum and the definitive version is available at: http://www.scientific.net/MSF.879.1404
Version: Accepted for publication
DOI: 10.4028/www.scientific.net/MSF.879.1404
URI: https://dspace.lboro.ac.uk/2134/23910
Publisher Link: http://dx.doi.org/10.4028/www.scientific.net/MSF.879.1404
ISBN: 9783035711295
ISSN: 0255-5476
Appears in Collections:Conference Papers and Presentations (Mechanical, Electrical and Manufacturing Engineering)

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