March et al 2017 Intestinal barrier distrubances in heamodialysis patients mechanisms consequences and therapeutic options.pdf (1.32 MB)
Intestinal barrier disturbances in haemodialysis patients: Mechanisms, consequences, and therapeutic options
journal contribution
posted on 2017-02-09, 11:30 authored by Daniel S. March, Matthew P.M. Graham-Brown, C.M. Stover, Nicolette BishopNicolette Bishop, James O. BurtonThere is accumulating evidence that the intestinal barrier and the microbiota may play a role in the systemic inflammation present in HD patients. HD patients are subject to a number of unique factors, some related to the HD process and others simply to the uraemic milieu but with common characteristic that they can both alter the intestinal barrier and the microbiota. This review is intended to provide an overview of the current methods for measuring such changes in HD patients, the mechanisms behind these changes, and potential strategies that may mitigate these modifications. Lastly, intradialytic exercise is an increasingly employed intervention in HDpatients; however the potential implications that this may have for the intestinal barrier are not known; therefore future research directions are also covered.
History
School
- Sport, Exercise and Health Sciences
Published in
BioMed Research InternationalVolume
2017Pages
? - ? (11)Citation
MARCH, D.S. ...et al., 2017. Intestinal barrier disturbances in haemodialysis patients: Mechanisms, consequences, and therapeutic options. BioMed Research International, 2017: 5765417.Publisher
© The Authors. Published by the Hindawi Publishing CorporationVersion
- VoR (Version of Record)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution 4.0 International (CC BY 4.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/ by/4.0/Acceptance date
2016-12-20Publication date
2017Notes
This is an Open Access Article. It is published by Hinawi under the Creative Commons Attribution 4.0 Unported Licence (CC BY). Full details of this licence are available at: http://creativecommons.org/licenses/by/4.0/ISSN
2314-6141Publisher version
Language
- en