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Title: Intestinal barrier disturbances in haemodialysis patients: Mechanisms, consequences, and therapeutic options
Authors: March, Daniel S.
Graham-Brown, Matthew P.M.
Stover, C.M.
Bishop, Nicolette
Burton, James O.
Issue Date: 2017
Publisher: © The Authors. Published by the Hindawi Publishing Corporation
Citation: MARCH, D.S. ...et al., 2017. Intestinal barrier disturbances in haemodialysis patients: Mechanisms, consequences, and therapeutic options. BioMed Research International, 2017: 5765417.
Abstract: There is accumulating evidence that the intestinal barrier and the microbiota may play a role in the systemic inflammation present in HD patients. HD patients are subject to a number of unique factors, some related to the HD process and others simply to the uraemic milieu but with common characteristic that they can both alter the intestinal barrier and the microbiota. This review is intended to provide an overview of the current methods for measuring such changes in HD patients, the mechanisms behind these changes, and potential strategies that may mitigate these modifications. Lastly, intradialytic exercise is an increasingly employed intervention in HDpatients; however the potential implications that this may have for the intestinal barrier are not known; therefore future research directions are also covered.
Description: This is an Open Access Article. It is published by Hinawi under the Creative Commons Attribution 4.0 Unported Licence (CC BY). Full details of this licence are available at: http://creativecommons.org/licenses/by/4.0/
Version: Published
DOI: 10.1155/2017/5765417
URI: https://dspace.lboro.ac.uk/2134/24050
Publisher Link: http://dx.doi.org/10.1155/2017/5765417
ISSN: 2314-6141
Appears in Collections:Published Articles (Sport, Exercise and Health Sciences)

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